井穴和耳尖放血治疗新型冠状病毒感染无症状及轻症外感风热证咽痛患者回顾性队列研究  

Retrospective Cohort Study of Jing-Point and Auricular Tip Bloodletting for Exogenous Wind-Heat Sore Syndrome Throat in Asymptomatic and Mild SARS-CoV-2 Infection Patients

作　　者：孟家乐 袁思成 王毅军 藕二祥 陈剑 武强 汪媛媛 郭涛 MENG Jia-le;YUAN Si-cheng;WANG Yi-jun;OU Er-xiang;CHEN Jian;WU Qiang;WANG Yuan-yuan;GUO Tao(Department of Emergency,Atfiliated Hospital of Nanjing University of Chinese Medicine,Nanjing,210000)

机构地区：[1]南京中医药大学附属医院急诊科,南京210000

出　　处：《中国中西医结合杂志》2023年第4期410-414,共5页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：目的观察井穴和耳尖放血对新型冠状(简称新冠)病毒感染咽痛患者的止痛疗效。方法采取回顾性队列研究的方法,收集515例新冠病毒感染无症状及轻症外感风热证咽痛患者。依据患者是否接受中医井穴和耳尖放血分为试验组(165例)和对照组(350例),利用病程、疼痛评分、基础病进行倾向性匹配后,最终试验组和对照组各纳入155例。对照组予常规治疗,试验组在对照组的基础上,给予井穴(少商、商阳)和耳尖放血疗法治疗1次。采用视觉模拟评分(VAS)评价治疗前及治疗后30、60、120 min的疼痛情况,评价30、60 min止痛效率,记录止痛起效时间;测量治疗前及治疗48 h后血超敏C反应蛋白(hs-CRP)、肿瘤坏死因子-α(TNF-α)、白介素-6(IL-6)水平。结果与本组治疗前比较,两组治疗后30、60、120 min VAS评分及血hs-CRP、TNF-α、IL-6水平下降(P<0.01)。与对照组同期比较,试验组治疗后30、60、120 min VAS评分及平均止痛时间下降(P<0.01),30、60 min止痛效率升高(P<0.01)。两组治疗前、后hs-CRP、TNF-α、IL-6比较,差异均无统计学意义(P>0.05)。结论井穴和耳尖放血可有效且快速改善新冠引起的咽喉疼痛。Objective To observe the analgesic effect of Jing-point and auricular tip bloodletting for sore throat patients with SARS-CoV-2 infection.Methods Totally 515 exogenous wind-heat sore syndrome throat in asymptomatic and mild SARS-CoV-2 infection patients were recruited by a retrospective cohort study.The patients were assigned to experimental group(165 cases)and control group(350 cases)based on whether or not accectping jing-point and auricular tip bloodletting.After propensity score matching using disease duration,pain score and underlying diseases,155 cases in each group were finally included.The control group received conventional treatment,the experimental group received jing-point[including Shaoshang(LU11)and Shangyang(LI1)]and auricular tip bloodletting once combined with conventional treatment.Visual analogue scale(VAS)was used to evaluate the condition of pain before treatment and 30,60,120 min after treatment.The 30 and 60 min efficiency of pain relief was evaluated.Onset time of pain relief was recorded.The blood hypersensitive C-reactive protein(hs-CRP),tumour necrosis factor-α(TNF-α),interleukin-6(IL-6)was measured before and 48 h after treatment.Results Compared with baseline,30,60,120 min VAS,level of blood hs-CRP,TNF-α,IL-6 decreased in 2 groups after treatment(P<0.01).Compared with the control group in the same time,30,60,120 min VAS,mean time of pain relief decreased(P<0.01),30 and 60 min efficiency of pain relief increased in experimental group after treatment(P<0.01).There was no statistical significance in level of blood hs-CRP,TNF-αand IL-6 between the 2 groups before and after treatment(P>0.05).Conclusion Jing-point and auricular tip bloodletting can effectively and quickly relieve sore throat caused by SARS-CoV-2 infection.

关 键 词：井穴 耳尖 放血 新型冠状病毒感染 咽喉疼痛 回顾性队列研究 

分 类 号：R246.1[医药卫生—针灸推拿学]