新型抗生素替代品抗菌肽在畜禽养殖上的应用  

Application of Antimicrobial Peptides as New Antibiotic Substitutes in Livestock and Poultry Breeding

作　　者：张利 华松 ZHANG Li;HUA Song(Fugu Animal Disease Prevention and Control Center,Yulin,Shaanxi,719400,China;College of Veterinary Medicine,Northwest A&F University,Yangling,Shaanxi 712100,China)

机构地区：[1]陕西省榆林市府谷县动物疫病预防控制中心,陕西榆林719400 [2]西北农林科技大学动物医学院

出　　处：《畜牧兽医杂志》2023年第3期120-122,共3页Journal of Animal Science and Veterinary Medicine

基　　金：黄河流域(榆林段)畜禽养殖污染源治理关键技术研究与示范[YF-2021-195]。

摘　　要：抗菌肽又称抗微生物肽,是生物先天性免疫的重要组成成份,具有广谱抗菌作用并且不易产生耐药性。抗菌肽作为饲料添加剂有促生长、防病以及可提高机体免疫力的作用;作为兽药可治疗各类细菌性、病毒性疾病以及各类寄生虫疾病;抗菌肽在畜禽养殖上的功能正在逐渐被开发,有望被开发成为抗生素替代品而广泛应用于畜禽养殖业。本文就家畜来源的抗菌肽从结构、用途和作用机制以及在畜牧兽医领域中的应用进行系统的分析与讨论。Antimicrobial peptides,also known as antimicrobial peptides,are important components of biological innate immunity.It has a broad-spectrum antibacterial effect and is not prone to drug resistance.As a feed additive,antimicrobial peptides can promote growth,prevent diseases and improve the body's immunity.As a veterinary drug,it can treat various bacterial and viral diseases and various parasitic diseases.The function of antimicrobial peptides in livestock and poultry farming is gradually being developed,which is expected to be developed as a substitute for antibiotics and widely used in livestock and poultry farming.This article systematically analyzes and discusses the antimicrobial peptides derived from livestock from the structure,use and mechanism of action,as well as their application in the field of animal husbandry and veterinary medicine.

关 键 词：抗菌肽 疾病预防 疾病治疗 免疫调节 无抗养殖 

分 类 号：S816.73[农业科学—饲料科学]