骨化性气管支气管病介入治疗1例并文献复习  

Tracheobronchopathia osteochondroplastica treated by bronchoscopic interventions:a case report and literature review

作　　者：江胜利 张琦 詹枝华 罗田应[1] JIANG Shengli;ZHANG Qi;ZHAN Zhihua;LUO Tianying(Department of Respiratory and Critical Care Medicine,People's Hospital of MaCheng City,Hubei Province,Macheng 438300,China;Department of Otorhinolaryngology,People's Hospital of MaCheng City,Hubei Province,Macheng 438300,China)

机构地区：[1]湖北省麻城市人民医院呼吸与危重症医学科,湖北麻城438300 [2]湖北省麻城市人民医院眼耳鼻喉科,湖北麻城438300

出　　处：《中国当代医药》2023年第15期149-152,共4页China Modern Medicine

摘　　要：骨化性气管支气管病(TO)是一种病因不明的少见良性疾病,其特征是在气管或支气管的黏膜下层形成多个软骨或骨性结节突向管腔,典型病例通过胸部CT、支气管镜下表现即可诊断,但典型表现并不常有,孤立病灶更少见,且该病无特异性症状,医生对该病认识不足,常被误诊为其他疾病或延迟诊断。本文为提升TO诊断能力,对1例TO患者的诊断与治疗过程进行整理分析,并对相关文献进行总结。该例TO患者胸部CT与支气管镜下表现均不典型且无临床特异性症状,行增强CT了解结节血供后给予镜下活检并进行冷冻治疗,病理检查发现板层骨及造血现象得以确诊,在支气管镜下介入治疗取得良好疗效。可见病理活检对非典型TO的明确诊断具有重要价值,支气管镜下介入处理既有助于诊断也是治疗手段。Tracheobronchopathia osteochondroplastica(TO)is an extremely rare,benign disease of uncertain etiology characterized by the formation of multiple cartilaginous or osseous nodules that grow into the airway lumen in the submucosal layer of the trachea or larger bronchi.According to the typical bronchoscopic visualization and the chest computed tomography(CT)scan,TO can be relatively easy diagnosed.But TO is not always an easily recognized disease,isolatedness lesion is less often realized,besides,the non-specific symptomology and lack of awareness,which is frequently confused with other diagnoses or diagnosis is delayed.The purpose of this report is to enhance the diagnostic ability of TO.The diagnosis and treatment strategy of a patient with TO were analyzed,and the relevant literatures were reviewed to deepen the knowledge of TO.In the current study,the patient showed non-specific symptoms,and that,bronchoscopic appearance and chest computed tomography(CT)scan revealed atypical.So,contrast-enhanced CT was performed to understand the blood supply of the nodules,and then the solitary nodule blocked lobar bronchus was removed with the help of bronchoscopic biopsy and cryotherapy,in the end,mature bone tissue and hematopoiesis could be seen through histopathological examination of biopsy,which confirmed the case.The man benefited significantly from bronchoscopic intervention.Pathology is of great value for definite diagnosis of atypical case.This article emphasizes interventional bronchoscopy is helpful for both diagnosis and management.

关 键 词：骨化性气管支气管病 支气管镜 介入治疗 冷冻治疗 

分 类 号：R562.2[医药卫生—呼吸系统]