脂肪组织炎症对动物健康影响因素分析  

Influencing factors of adipose tissue inflammation on animal health

作　　者：柴金宝 王含琼 刘利[1] 王建发[2] 卜也 岳萌萌 孙芳[1] 武瑞[2] CHAI Jinbao;WANG Hanqiong;LIU Li;WANG Jianfa;BU Ye;YUE Mengmeng;SUN Fang;WU Rui(Institute of Animal Husbandry,Heilongjiang Academy of Agricultural Sciences,Harbin 150086,China;College of Animal Science and Veterinary Medicine,Heilongjiang Bayi Agricultural University,Daqing 163319,China;College of Animal Scienceand Technology,Northeast Agricultural University,Harbin 150030,China)

机构地区：[1]黑龙江省农业科学院畜牧研究所,哈尔滨150086 [2]黑龙江八一农垦大学动物科技学院,黑龙江大庆163319 [3]东北农业大学动物科学技术学院,哈尔滨150030

出　　处：《黑龙江畜牧兽医》2023年第9期33-37,共5页Heilongjiang Animal Science And veterinary Medicine

基　　金：国家肉牛牦牛产业技术体系建设项目(CARS37);黑龙江省现代农业产业技术协同创新推广体系建设项目(黑农厅函[2021]1492号);黑龙江省农业农村厅项目“畜牧技术推广专项”(23000021Y000000055567)。

摘　　要：脂肪过度沉积或脂肪细胞肥大可导致脂肪组织炎症,表现为脂肪代谢紊乱和慢性脂肪组织炎症,使动物生产性能降低。当动物机体发生慢性脂肪组织炎症时会产生大量巨噬细胞及miRNA,并释放各种炎症因子[肿瘤坏死因子α(TNF-α)、白细胞介素-1β(IL-1β)、白细胞介素-6(IL-6)],对机体肝脏、肌肉及其他器官或组织产生不利影响,使机体负担加重,引起各种疾病,造成不必要的经济损失。文章综述了脂肪组织炎症及其发展过程、动物脂肪代谢和脂肪组织炎症相关性,论述了脂肪组织炎症对动物机体各个器官产生的不利影响,以期为提高动物福利提供新的理论参考。Adipose tissue inflammation is caused by excessive deposition of fat or hypertrophy of adipose cells. It is manifested as fat metabolism disorder and chronic adipose tissue inflammation, which can reduce animal performance. When chronic adipose tissue inflammation occurs in the animal body, a large number of macrophages and mirnas are produced, and various inflammatory factors(TNF-α, IL-1β, IL-6) will be released, which will have adverse effects on the liver, muscle, and other organs or tissues, increase the burden on the body, cause various diseases, and cause unnecessary economic losses. This paper reviewed adipose tissue inflammation and its development process, and discussed the correlation between adipose tissue inflammation and animal fat metabolism, and discussed the adverse effects of adipose tissue inflammation on animal organs, in order to provide a new theoretical reference for animal health and welfare.

关 键 词：脂肪组织 炎症 炎症因子 肌肉 脂肪代谢 紊乱 

分 类 号：S813[农业科学—畜牧学] Q591.5[农业科学—畜牧兽医]