宫缩乏力性产后出血运用宫缩剂治疗的情况调查分析  

Investigation and Analysis of Contraction Agent in the Treatment of Postpartum Hemorrhage due to Uterine Inertia

作　　者：方春云 倪斌 姚细保[1] FANG Chunyun;NI Bin;YAO Xibao(The First Affiliated Hospital of Gannan Medical College,Ganzhou 341000,Jiangxi,China)

机构地区：[1]赣南医学院第一附属医院,江西赣州341000

出　　处：《现代诊断与治疗》2023年第4期475-477,共3页Modern Diagnosis and Treatment

基　　金：赣州市卫生健康委员会科研计划项目(项目编号2020-2-84)。

摘　　要：目的探讨治疗宫缩乏力性产后出血宫缩剂的使用情况及其疗效,为其合理运用提供参考。方法通过信息系统提取筛选2021年1月至12月我院收治的宫缩乏力性产后出血患者病历83例,将卡前列甲酯栓联合麦角新碱注射液治疗组14例纳入对照1组,卡前列甲酯栓联合卡前列素氨丁三醇注射液治疗组14例纳入对照2组,卡前列甲酯栓联合麦角新碱注射液及卡前列素氨丁三醇注射液治疗组55例纳入观察组。对宫缩剂使用情况进行回顾性分析,按照宫缩剂的使用情况进行分组,观察不同组别的止血效果、出血情况、血红蛋白下降情况等。结果观察组治疗有效率为98.12%,高于对照1组和对照2组,差异有统计学意义(P<0.05)。治疗前,观察组出血量高于对照1组和对照2组,差异有统计学意义(P<0.05);治疗后各时间段三组出血量比较,差异无统计学意义(P>0.05);55例未进行输血治疗的产妇平均下降(26.9±11.4)g/L,三组的Hb下降量比较,差异无统计学意义(P>0.05)。结论卡前列甲酯联用麦角新碱与卡前列素氨丁三醇对宫缩乏力性产后出血(特别出血量≥1000 ml)能够迅速止血,可用于产后大出血的抢救。Objective To explore the use and efficacy of uterine contraction agent in the treatment of postpartum hemorrhage due to uterine inertia,and to provide reference for its rational use.Methods The medical records of 83 patients with postpartum hemorrhage due to uterine inertia admitted to our hospital from January to December 2021 were extracted and screened through the information system.The 14 patients who received carboprost methylate suppository combined with ergometrine injection treatment were included in the control group 1,the 14 patients who received carboprost methylate suppository combined with carboprost tromethamine injection treatment were included in the control group 2,and the other 55 patients who received carboprost methylate suppository combined with ergometrine injection and carboprost tromethamine injection treatment were included in the observation group.The use of uterine contractions was analyzed retrospectively.According to the use of uterine contractions,the patients were divided into groups to observe the hemostatic effect,bleeding and hemoglobin decrease.Results The effective rate of treatment in the observation group was 98.12%,which was significantly higher than that in the control group 1 and the control group 2(P<0.05).Before treatment,the amount of bleeding in the observation group was significantly higher than that in the control group 1 and the control group 2(P<0.05).There was no significant difference in the amount of bleeding among the three groups at each time point after treatment(P>0.05).The average decrease of Hb of 55 parturients without blood transfusion was(26.9±11.4)g/L,and there was no statistically significant difference in terms of Hb decrease among the three groups(P>0.05).Conclusion Carboprost methylate combined with ergometrine and carboprost tromethamine can quickly stop bleeding in postpartum hemorrhage due to uterine inertia(especially when blood loss≥1000 ml),which can be used for the rescue of postpartum hemorrhage.

关 键 词：产后出血 宫缩乏力 宫缩剂 出血量 血红蛋白 

分 类 号：R714.4[医药卫生—妇产科学]