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作 者:王春燕[1] 辛成运 潘俊[1] 李腾[3] WANG Chunyan;XIN Chengyun;PAN Jun;LI Teng(Department of Otolaryngology,Peking University Shougang Hospital,Beijing 100144,China;School of Electrical and Power Engineering,China University of Mining and Technology,Xuzhou 221116,Jiangsu,China;Institute of Mechanics,Chinese Academy of Sciences,Beijing 100190,China)
机构地区:[1]北京大学首钢医院耳鼻喉科,北京100144 [2]中国矿业大学电气与动力工程学院,江苏徐州221116 [3]中国科学院力学研究所,北京100190
出 处:《力学与实践》2023年第2期409-417,共9页Mechanics in Engineering
基 金:北京大学首钢医院科研基金资助项目(SGYYZ201607)。
摘 要:根据真实人体喉气管CT影像数据构建了声门下喉气管狭窄的气道模型,并对这些模型进行了吸气条件下的计算流体力学仿真。分析比较了不同狭窄分度模型内的流场特征、不同喉气管部段的阻力特性以及喉气管壁面的压力与切应力分布,并对这些特性与临床病患表象的关联性进行了讨论。分析表明声门下喉气管狭窄分度与狭窄导致的呼吸道阻力变化具有良好的关联性,此外,喉气管狭窄处压力及剪应力效应对病程的影响也需要关注。In this paper,a 3D model of real human laryngotracheal airways was reconstructed based on computed tomography(CT)image data,and airway models with different subglottic laryngotracheal stenosis were then constructed.Computational fluid dynamics simulations under inspiratory conditions were performed on these airway models.The flow field characteristics of the laryngotracheal airway in different stenosis classification models,the resistance characteristics of different laryngotracheal segments,and the pressure and shear stress distribution of the flow field on the laryngotracheal wall were analyzed and compared.The correlation between these characteristics and clinical phenomena is discussed.The analysis showed that graduation is well correlated with the respiratory tract resistance caused by subglottic laryngeal tracheal stenosis;in addition,the negative airflow pressure and shear stress effect caused by laryngotracheal stenosis should be paid sufficient attention to the effect on the course of the disease in clinical treatment.
分 类 号:R318.01[医药卫生—生物医学工程]
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