中国仿制药替代影响因素分析--基于“4+7”带量采购精神科用药患者角度  

Influencing factors of generic drug substitution in China--from the perspective of psychiatric patients in“4+7”pilot cities

作　　者：刘文夏 马俊 杨照[3] 江滨[1] Wenxia Liu;Jun Ma;Zhao Yang;Bin Jiang(Department of Administrative and Clinical Pharmacy,School of Pharmaceutical Sciences,Peking University Health Science Center,Beijing 100191,China;Peking University Third Hospital,Beijing 100191,China;Office of Academic Research of Peking University First Hospital,Beijing 100034,China)

机构地区：[1]北京大学医学部药学院药事管理与临床药学系,北京100191 [2]北京大学第三医院,北京100091 [3]北京大学第一医院科研处,北京100034

出　　处：《Journal of Chinese Pharmaceutical Sciences》2023年第4期317-321,共5页中国药学（英文版）

基　　金：Beijing Natural Science Foundation(Grant No.9224039).

摘　　要：中国仿制药替代受到多种因素的影响,然而现有的研究主要集中在政策分析和临床使用上。本文旨在从“4+7”带量采购精神科用药患者角度,研究中国仿制药替代的影响因素。以问卷调研四个试点城市精神科患者的人口特征、使用中选仿制药意愿及影响因素等,并对其进行统计分析。研究发现,单因素影响分析中,使用中选仿制药意愿与患者教育水平、年龄、平均月收入、患病时间、患病程度显著相关;影响因素回归分析中,使用中选仿制药意愿与患者年龄显著相关。因此,政府应当重视中青年群体在仿制药替代中的作用,进行差异化管理,加强对各方人士的教育宣传,调整中选仿制药的医保支付标准,要求医生对目标患者提出使用中选仿制药建议。In China,generic drug substitution is affected by multiple factors.However,existing studies mainly focus on policy analysis and clinical use.Therefore,we aimed to investigate the influencing factors in psychiatric patients in China’s“4+7”pilot cities.The demographic characteristics,willingness to use Chinese generic drugs,and influencing factors of psychiatric patients in four pilot cities were investigated by questionnaire,and the results were statistically analyzed.Univariate analysis revealed that the willingness to use the selected generic drugs was significantly correlated with educational background,age,average monthly income,time of illness,and severity of illness.Furthermore,logistic regression analysis indicated that the willingness to use the selected generic drugs was significantly associated with patients’age.Therefore,the government should pay attention to the role of young and middle-aged groups in the substitution of generic drugs,carry out differential management,strengthen education and propaganda to all parties,adjust the standard of medical insurance payment for the selected generic drugs,and ask doctors to make suggestions on the use of selected generic drugs to target patients.

关 键 词：仿制药替代 影响因素 带量采购 精神科用药 

分 类 号：R954[医药卫生—药学]