薏苡仁油对过度运动大鼠的抗疲劳作用及免疫功能改善效果的研究  

Anti-fatigue and Immune Function Improvement of Coix Seed Oil on Excessive Exercise Rats

作　　者：郭云聪 GUO Yuncong(College of Continuing Education,Yunnan Normal University,Kunming 650092,China)

机构地区：[1]云南师范大学继续教育学院,云南昆明650092

出　　处：《家畜生态学报》2023年第5期59-64,共6页Journal of Domestic Animal Ecology

基　　金：教育部国际合作与交流课题(S2012009);云南省教育厅课题(S2012009)。

摘　　要：试验旨在研究薏苡仁油对过度运动大鼠的抗疲劳作用及免疫功能改善效果的研究。将SD大鼠随机分为对照组、过度运动组及薏苡仁油低、高剂量组(0.60、1.20 g/kg/d),灌胃给予薏苡仁油,每天1次;同时,除对照组外,其余各组大鼠均给予过度运动训练。结果表明,与过度运动组比较,薏苡仁油低、高剂量组大鼠体质量、肝糖原、肌糖原含量、胸腺指数、脾脏指数、血清免疫球蛋白A(IgA)、IgG、IgM、干扰素γ(IFN-γ)、肿瘤坏死因子α(TNF-α)、白细胞介素2(IL-2)含量、脾脏B、T淋巴细胞增殖刺激指数、CD_(4)^(+)、CD_(8)^(+)T细胞比例及CD_(4)^(+)/CD_(8)^(+)比值均增加(P<0.05,P<0.01),血尿素氮(BUN)及血清IL-4、IL-10含量降低(P<0.01)。研究结果显示,薏苡仁油对过度运动大鼠具有抗疲劳作用,其机制与免疫功能改善有关。The aim of this experiment was to study the effects of coix seed oil(CSO)on anti-fatigue and improving immune function in excessive exercise(EE)rats.SD rats were randomly divided into control(CON)group,EE group,low dose of CSO(L-CSO)and high dose of CSO(H-CSO)groups(0.60,1.20 g/kg/d),and the CSO was administered by gavage once a day.At the same time,except for the CON group,rats in other groups were given EE training.The results showed that compared with those in the EE group,body mass,hepatic glycogen and muscle glycogen contents,thymus index,spleen index,serum immune globulin A(IgA),IgG,IgM,interferon γ(IFN-γ),tumor necrosis factorα(TNF-α)and interleukin-2(IL-2)contents,B and T lymphocyte proliferation stimulation index,the proportion of CD_(4)^(+)and CD_(8)^(+)T cell and CD_(4)^(+)/CD_(8)^(+)ratio increased(P<0.05,P<0.01)in the L-CSO and H-CSO groups,blood urea nitrogen(BUN)and serum IL-4 and IL-10 contents decreased(P<0.01).It is concluded that CSO has anti-fatigue effect in EE rats,and its mechanism may be related to improving immune function.

关 键 词：薏苡仁油 过度运动 抗疲劳 免疫功能 

分 类 号：S816.7[农业科学—饲料科学]