高蛋白饮食联合生活方式干预对肥胖患者体重控制及糖脂代谢的影响  

Effect of High Protein Diet Combined with Lifestyle Intervention on Weight Control and Glucolipid Metabolism in Obese Patients

作　　者：曹崇艳[1] 董永丽[2] CAO Chong-yan;DONG Yong-li(Department of Nutrition and Nutrition,Wangjing Hospital,China Academy of Chinese Medical Sciences,Beijing 100102,China;Department of Scientific Research,Wangjing Hospital,China Academy of Chinese Medical Sciences,Beijing 100102,China)

机构地区：[1]中国中医科学院望京医院营养食疗科,北京100102 [2]中国中医科学院望京医院科研处,北京100102

出　　处：《中国食物与营养》2023年第5期69-72,共4页Food and Nutrition in China

摘　　要：目的:探究高蛋白饮食模式联合生活方式干预对肥胖患者体重控制及糖、脂代谢的影响。方法:选取2021年4月—2022年6月在中国中医科学院望京医院营养科就诊,且接受医学减重治疗的93例肥胖患者为研究对象。对肥胖患者行高蛋白饮食和体育锻炼、行为干预,收集患者干预前和干预1个月后、干预6个月后体重、身高、腰围、臀围指标,以及血清总胆固醇(TC)、甘油三脂(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、空腹血糖(FPG)、空腹胰岛素(FINS),比较干预前和干预后体质指数(BMI)、腰臀比以及血清糖脂代谢指标的变化。结果:经高蛋白饮食联合生活方式干预后,患者BMI及腰臀比较治疗前显著降低(P<0.05),干预6个月改善情况优于1个月。另外,干预后患者血清TC、TG、HDL-C、LDL-C、FPG及FINS水平均较干预前显著降低(P<0.05),且干预6个月后,下降水平更为显著(P<0.05)。结论:对肥胖患者实施高蛋白饮食联合体育锻炼等生活方式干预,可有效降低患者体重,改善患者中心性肥胖情况和糖脂代谢。Objective To investigate the effects of a high-protein dietary pattern combined with lifestyle intervention on weight control and glucose and lipid metabolism in obese patients.Method Totally 93 obese patients who attended the Department of Clinical Nutrition of Wangjing Hospital,Chinese Academy of Traditional Chinese Medicine from April 2021 to June 2022 and received medical weight loss treatment were selected for this study.The obese patients were subjected to high protein diet and physical exercise and behavioral interventions,and the weight,height,waist circumference,hip circumference indexes,as well as serum total cholesterol(TC),triglyceride(TG),high-density lipoprotein cholesterol(HDL-C)and low-density lipoprotein cholesterol(LDL-C),fasting blood glucose(FPG)and fasting insulin(FINS),and compare the changes of body mass index(BMI),waist-to-hip ratio and serum glucolipid metabolism indexes before and after the intervention.Result After the high-protein diet combined with lifestyle intervention,patients had significantly lower BMI and waist-hip compared to pre-treatment(P<0.05),and the improvement was better at 6 months of intervention than at 1 month.In addition,serum TC,TG,HDL-C,LDL-C,FPG and FINS levels were significantly lower in patients after the intervention than before the intervention(P<0.05),and the level of decrease was more significant after 6 months of the intervention(P<0.05).Conclusion Lifestyle interventions such as high-protein diet combined with physical exercise in obese patients can effectively reduce their body weight and improve their central obesity profile and glucolipid metabolism.

关 键 词：高蛋白饮食 肥胖 体重 糖脂代谢 

分 类 号：R589.2[医药卫生—内分泌]