刚性近壁面靶向微泡的声学特性分析  

Analysis of Acoustic Characteristics of Rigid Near Wall Target Microbubbles

作　　者：陈颖明 CHEN Ying-ming(College of Mathematics and Physics,Inner Mongolia Minzu University,Tongliao 028043,China)

机构地区：[1]内蒙古民族大学数理学院,内蒙古通辽028043

出　　处：《内蒙古民族大学学报（自然科学版）》2023年第3期205-208,219,共5页Journal of Inner Mongolia Minzu University：Natural Sciences

基　　金：国家自然科学基金项目(11462019)。

摘　　要：考虑靶向微泡包膜黏性项的非线性影响,引入NSEV模型,得到了靶向包膜微泡的振动方程。基于此模型,分析了微泡初始半径、驱动频率、驱动声压对微泡声学特性的影响。数值分析结果表明:微泡的最大半径、最小半径、仅压缩系数、正向最大散射声压值和负向最大散射声压值在较高驱动声压、驱动频率下的数值更大,散射特性更加明显;探究黏性项对微泡的声学特性的影响将对医用靶向药物治疗以及术后治疗效果评估等提供更符合实际的理论模型,同时为寻找更适于人体器官组织安全的造影条件提供理论参考依据。Considering the nonlinear influence of viscosity term of the targeted microbubble,NSEV model was in⁃troduced,and the vibration equation of the targeted microbubble was obtained.Based on this model,the effects of initial radius,driving frequency and driving sound pressure on the acoustic characteristics of microbubble were analyzed.The numerical analysis results show that the maximum radius,minimum radius,compression coefficient only,positive maximum scattering sound pressure,and negative maximum scattering sound pressure of microbub⁃ble have larger values at higher driving sound pressure and driving frequency,and the scattering characteristics are more obvious.Exploring the influence of viscous term on the acoustic properties of microbubbles will provide a more practical theoretical model for medical targeted drug therapy and postoperative evaluation of therapeutic effect,and provide a theoretical reference for finding a more suitable imaging condition for the safety of human or⁃gans and tissues.

关 键 词：修正的MARMOTTANT模型 黏性 NSEV模型 

分 类 号：O411[理学—理论物理]