机器人辅助腹腔镜手术与开腹手术治疗早期宫颈癌术后生存影响因素的对比分析  

Comparative analysis on the influencing factors of postoperative survival between robot-assisted laparoscopic surgery and laparotomy in the treatment of early cervical cancer

作　　者：周潇妮 张琦玲 蔡丽萍[2] 涂春华[2] 张智[2] 唐旭秀 肖子文 赵娜 ZHOU Xiaoni;ZHANG Qiling;CAI Liping;TU Chunhua;ZHANG Zhi;TANG Xuxiu;XIAO Ziwen;ZHAO Na(Department of Gynecology,the Second People’s Hospital of Jingdezhen,Jingdezhen 333000,China;Department of Obstetrics and Gynecology,the First Affiliated Hospital of Nanchang University,Nanchang 330000,China;The First Clinical Medical College of Nanchang University,Nanchang 330000,China;Department of Clinical Laboratory,the Second People’s Hospital of Laboratory Jingdezhen,Jingdezhen 333000,China)

机构地区：[1]景德镇市第二人民医院妇科,江西景德镇333000 [2]南昌大学第一附属医院妇产科,江西南昌330000 [3]南昌大学第一临床医学院,江西南昌330000 [4]景德镇市第二人民医院检验科,江西景德镇333000

出　　处：《机器人外科学杂志（中英文）》2023年第5期431-440,共10页Chinese Journal of Robotic Surgery

基　　金：江西省自然科学基金(20192ACBL20038);江西省科技计划重大项目(20152ACG70022);江西省卫生计生委中医药科研计划(2020Z001)。

摘　　要：目的:分析早期宫颈癌患者行机器人辅助腹腔镜手术与开腹手术对其术后生存质量的影响及其相关因素,并进行对比。方法:回顾性分析2016年1月—2021年6月于南昌大学第一附属医院妇科接受治疗的904例早期宫颈癌患者的临床资料。其中研究组为机器人手术组,共413例,患者全部行机器人辅助子宫切除术及盆腔淋巴结清扫术,并对部分患者行腹主动脉旁淋巴结取样;对照组为开腹手术组,共491例,行开腹子宫切除术及盆腔淋巴结清扫术,并对部分患者行腹主动脉旁淋巴结取样。结果:研究组与对照组的一般临床特征相比,差异无统计学意义(P>0.05),但两组术后多项手术质量评价指标(如并发症等)比较,差异有统计学意义(P<0.05)。两组在病理预后因素以及总生存期、无病生存期的对比中并无明显统计学差异(P>0.05)。结论:与开腹手术相比,机器人辅助手术治疗早期宫颈癌患者的手术质量评价较好,但在患者病理预后因素及术后生存期上无明显改善。Objective:To compare and analyze the quality of life of patients underwent robot-assisted laparoscopic surgery and laparotomy for early cervical cancer and and its related factors.Methods:A retrospective study was performed on 904 patients with early cervical cancer who were treated in the Department of Gynecology,the First Affiliated Hospital of Nanchang University from January 2016 to June 2021.The study group(robotic surgery group)had a total of 413 cases,all patients underwent robot-assisted hysterectomy and pelvic lymph node dissection,and some patients underwent abdominal aortic lymph node sampling.The control group(laparotomy group)had a total of 491 cases,laparotomy for hysterectomy and pelvic lymph node dissection was performed,and para-aortic lymph node sampling was performed in some patients.Results:There was no significant difference in general clinical characteristics between the study group and the control group(P>0.05),but several postoperative surgical quality evaluation indicators(such as complications)in the study group were significantly different from those in the control group(P<0.05).In addition,there was no significant difference in the comparison of pathological prognostic factors,overall survival and disease-free survival between the two groups(P>0.05).Conclusion:For patients with early cervical cancer,compared with the laparotomy,robotic surgery has better surgical quality evaluation,but there is no significant improvement in terms of pathological prognostic factors and postoperative survival.

关 键 词：早期宫颈癌 机器人辅助手术 开腹手术 总生存期 无病生存期 

分 类 号：R608[医药卫生—外科学] R713[医药卫生—临床医学]