血小板减少对危重患者连续性肾脏替代治疗后感染的影响  

Effect of thrombocytopenia on infection after continuous renal replacement therapy in critically ill patients

作　　者：胡太松 李霞[2] 王矩伟[1] HU Tai-song;LI Xia;WANG Ju-wei(Intensive Care Medicine,Puyang Oilfield General Hospital,Puyang,Henan 457001,China;Department of Function,Puyang Oilfield General Hospital,Puyang,Henan 457001,China)

机构地区：[1]濮阳市油田总医院重症医学科,河南濮阳457001 [2]濮阳市油田总医院功能科,河南濮阳457001

出　　处：《医药论坛杂志》2023年第7期37-40,45,共5页Journal of Medical Forum

摘　　要：目的 探讨血小板降低对患者连续性肾脏替代治疗(CRRT)后临床结局的影响。方法 应用回顾性队列研究方法,根据患者血小板降低状况将其分为血小板降低≤40%组和血小板降低>40%组。对比分析两组患者的一般资料及临床结局,应用logistic回归分析探讨血小板降低幅度对患者临床结局的影响。结果 年龄大、总住院时间长、糖尿病史、血小板降低>40%是患者感染的危险因素;年龄大、糖尿病史、血小板降低>40%是患者感染性休克的危险因素;年龄大、多器官功能衰竭、ICU住院时间长、血小板降低>40%是患者死亡的危险因素。结论 CRRT后血小板计数降低幅度过大会增加危重患者感染、感染性休克、死亡的风险。Objective To investigate the effect of thrombocytopenia on the clinical outcome of patients after continuous renal replacement(CRRT).Methods Retrospective cohort study was used.According to the status of thrombocytopenia,patients were divided into thrombocytopenia ≤ 40% group and thrombocytopenia 40% group.The general data and clinical outcomes of the two groups were compared and analyzed.logistic regression analysis was used to explore the effect of thrombocytopenia on the clinical outcome.Results Age,length of stay,history of diabetes and thrombocytopenia(40%) were risk factors for infection.Age,diabetes and thrombocytopenia 40% were risk factors for septic shock.Older age,multiple organ failure,long ICU stay and thrombocytopenia 40% were the risk factors of death.Conclusion Excessive reduction of platelet count after CRRT increases the risk of infection,septic shock and death in critically ill patients.

关 键 词：血小板 肾脏替代治疗 感染 影响 

分 类 号：R692[医药卫生—泌尿科学]