Evaluation of children and adults with post-COVID-19 persistent smell,taste and trigeminal chemosensory disorders:A hospital based study  

作　　者：Sherifa Ahmed Hamed Eman Bahaa Kamal-Eldeen Mohamed Azzam Abdel-Razek Ahmed 

机构地区：[1]Department of Neurology and Psychiatry,Assiut University,Faculty of Medicine,Assiut 71516,Egypt [2]Department of Pediatrics,Assiut University,Faculty of Medicine,Assiut 71516,Egypt [3]Department of ENT,Assiut University,Faculty of Medicine,Assiut 71516,Egypt

出　　处：《World Journal of Clinical Pediatrics》2023年第3期133-150,共18页世界临床儿科杂志

摘　　要：BACKGROUND Smell disorders are the most frequent persistent coronavirus disease 2019(COVID-19)complications.AIM To describe the patterns and characteristics of persistent smell and taste disorders in Egyptian patients.METHODS Assessment was done to 185 patients(adults=150,age:31.41±8.63 years;children=35;age:15.66±1.63 years).Otolaryngology and neuropsychiatric evaluations were done.Measurements included:A clinical questionnaire(for smell and taste);sniffin'odor,taste and flavor identification tests and the Questionnaire of Olfactory Disorders-Negative Statements(sQOD-NS).RESULTS Duration of disorders was 11.53±3.97 ms(6-24 ms).Parosmia(n=119;64.32%)was developed months after anosmia(3.05±1.87 ms).Objective testing showed anosmia in all,ageusia and flavor loss in 20%(n=37)and loss of nasal and oral trigeminal sensations in 18%(n=33)and 20%(n=37),respectively.Patients had low scoring of sQOD-NS(11.41±3.66).There were no specific differences in other demographics and clinical variables which could distinguish post-COVID-19 smell and taste disorders in children from adults.CONCLUSION The course of small and taste disorders are supportive of the nasal and oral neuronal compromises.Post-COVID-19 taste and trigeminal disorders were less frequent compared to smell disorders.Post-COVID-19 flavor disorders were solely dependent on taste and not smell disorders.There were no demographics,clinical variables at onset or specific profile of these disorders in children compared to adults.

关 键 词：Post-COVID-19 complications ANOSMIA AGEUSIA Trigeminal sensory loss Parosmia Quality of life 

分 类 号：R725.6[医药卫生—儿科]