Prevotella oris-caused meningitis and spinal canal infection:A case report  

作　　者：Wei-Wei Zhang Chao Ai Chien-Tai Mao Dong-Kang Liu Yi Guo 

机构地区：[1]Department of Clinical Pharmacy,Beijing Tsinghua Changgung Hospital,School of Medicine,Tsinghua University,Beijing 102218,China [2]Department of Neurosurgery,Beijing Tsinghua Changgung Hospital,School of Medicine,Tsinghua University,Beijing 102218,China

出　　处：《World Journal of Clinical Cases》2023年第16期3830-3836,共7页世界临床病例杂志

摘　　要：BACKGROUND Prevotella oris-induced meningitis and Prevotella oris-induced meningitis concomitant with spinal canal infection are extremely rare.To the best of our knowledge,only 1 case of Prevotella oris-induced central system infection has been reported.This is the second report on meningitis combined with spinal canal infection due to Prevotella oris.CASE SUMMARY We report a case of a 9-year-old boy suffering from meningitis and spinal canal infection.The patient presented to the neurosurgery department with lumbosacral pain for 1 mo and headache and vomiting for 1 d.He had been treated with cephalosporin and nonsteroidal anti-inflammatory drugs for fever,otalgia and pharyngalgia in a local hospital 2 mo prior to this admission.During hospitalization,magnetic resonance imaging suggested meningitis and L3-S1 lumbosacral dural sac infection.The cerebrospinal fluid and blood cultures were negative,but the cerebrospinal fluid specimen indicated the presence of Prevotella oris by metagenomic next-generation sequencing.Previous cases of Prevotella oris infection were retrieved from PubMed to characterize the clinicopathological features and identify the prognostic factors and related antimicrobial treatment of infection due to Prevotella oris.CONCLUSION This report shed light on the characteristics of Prevotella oris infection and highlighted the role of metagenomic next-generation sequencing in pathogen detection.

关 键 词：Prevotella oris MENINGITIS Spinal canal infection Metagenomic next-generation sequencing Central nervous system infection Case report 

分 类 号：R725.1[医药卫生—儿科]