慢性阻塞性肺疾病中小气道病变的研究进展  

Research progress on small airway lesions in chronic obstructive pulmonary disease

作　　者：卢意 熊简 李雪寒 LU Yi;XIONG Jian;LI Xuehan(The First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China;Sichuan University,Chendu,Sichuan 610065)

机构地区：[1]重庆医科大学附属第一医院,重庆400016 [2]四川大学,四川成都610065

出　　处：《徐州医科大学学报》2023年第5期385-390,共6页Journal of Xuzhou Medical University

基　　金：四川省自然科学基金青年项目(81900064)。

摘　　要：小气道是慢性阻塞性肺疾病的关键病变部位,在尚未发展至慢性阻塞性肺疾病时就已存在小气道病变,但因为缺乏临床症状及系统的诊疗方法常常被忽视。近年来,小气道病变受到越来越多的重视,早期发现、早期治疗小气道病变,对于延缓疾病发展及改善预后至关重要,本文针对目前慢性阻塞性肺疾病中小气道病变的病理、评估及治疗进展做一综述,为临床治疗及后续的研究方向提供思路。The small airways of the lungsare a key lesion site of chronic obstructive pulmonary disease,which has existed before the disease progresses tochronic obstructive pulmonary disease.However,this site is often overlooked due to the lack of clinical symptoms and systematic diagnosis and treatment.In recent years,small airway diseases have attracted more and more attention.Early detection and treatment of small airways are crucial for slowing down the progression of diseases and improving prognosis.This paper reviews the pathology,evaluation and treatment of small airways inchronic obstructive pulmonary disease,providing thoughts for clinical treatment and subsequent research direction.

关 键 词：慢性阻塞性肺疾病 小气道 肺功能 氮呼气试验 脉冲震荡法 高分辨率CT 超细吸入剂 

分 类 号：R563.[医药卫生—呼吸系统]