中国睡眠医学的过去、现在和未来  

The past,present and future of sleep medicine in China

作　　者：邓佳慧[1] 黄筱琳 刘晓星 孙杰[2] 陆林[1,3,4] DENG Jia-hui;HUANG Xiao-lin;LIU Xiao-xing;SUN Jie;LU Lin(Peking University Sixth Hospital,Peking University Institute of Mental Health,NHC Key Laboratory of Mental Health(Peking University),National Clinical Research Center for Mental Disorders(Peking University Sixth Hospital),Beijing 100191,China;Pain Medicine Center,Peking University Third Hospital,Bejjng 100191,China;Center for Life Sciences.,Academy for Advanced Interdiseiplinary Studies,Peking University,Bejing 100871,China;National Institu-te on Drug Dependence,Peking University&Bejjing Key Laboratory of Drug Dependence Research,Beijing 100191,China)

机构地区：[1]北京大学第六医院,北京大学精神卫生研究所,国家卫生健康委员会精神卫生学重点实验室(北京大学),国家精神心理疾病临床医学研究中心(北京大学第六医院),北京100191 [2]北京大学第三医院疼痛医学中心,北京100191 [3]北京大学前沿交叉学科研究院生命科学联合中心,北京100871 [4]北京大学中国药物依赖性研究所,药物依赖性研究北京市重点实验室,北京100191

出　　处：《北京大学学报（医学版）》2023年第3期567-572,F0003,共7页Journal of Peking University:Health Sciences

基　　金：国家自然科学基金(82271528)。

摘　　要：睡眠是生物进化过程中最基本的生命过程,占据人生约三分之一的时间,是人类生活最重要的组成部分^([1])。人类睡眠主要分为快速眼动(rapid eye movement,REM)睡眠和非快速眼动(non-rapid eye movement,NREM)睡眠,以大约90~100 min为一个周期出现NREM睡眠到REM睡眠的交替循环^([2])。睡眠对机体能量代谢、免疫调节、内分泌及脑功能活动等生理机能发挥重要调控作用.SUMMARY Sleep is a highly conserved phenomenon in endotherms,and has a universal physiological function across all species.In mammals,sleep can be divided into two stages:rapid eye movement(REM)sleep and non-REM(NREM)sleep,which alternate in a cyclic manner.Humans spend about one-third of their lives asleep.Sufficient sleep is necessary for humans to sustain everyday functioning.Sleep plays an important role in regulating energy metabolism,immune defense,endocrine function,and the consolidation of memory process.With the development of social economy and the change of life style,sleep duration of the residents has gradually decreased and the incidence of sleep disturbances has increased.Sleep disturbances can lead to severe mental disorders,such as depression,anxiety disorders,dementia,and other mental diseases,and may increase the risk of physical diseases,such as chronic in-flammation,heart disease,diabetes,hypertension,atherosclerosis and others.Maintaining good sleep is of great significance for developing social productive forces,promoting sustainable development of eco-nomic society,and is a necessary condition for carrying out the“Healthy China Strategy”.The sleep re-search in China started in 1950s.After decades of development,researchers have made great progress in the molecular mechanisms of sleep and wakefulness,the pathogenesis of sleep disorders and the develop-ment of new therapies.With the advancement of science and technology and the public’s attention to sleep,the level of clinical diagnosis and therapy of sleep disorders in China is gradually brought in line with international standards.The publication of diagnosis and treatment guidelines in the field of sleep medicine will promote the standardization of the construction.In the future,it is still necessary to pro-mote the development of sleep medicine in the following aspects:Strengthening the professional training and discipline construction,improving the cooperation of sleep research,promoting the intelligent diagno-sis and treatment of

关 键 词：睡眠医学 睡眠障碍 中国 研究进展 

分 类 号：R338.63[医药卫生—人体生理学]