维生素E稳定型高交联聚乙烯人工膝关节磨屑的分离提取  

Separation and extraction of wear debris of vitamin E-stabilized high cross-linked polyethylene artificial knee joints

作　　者：郑晔 黄秀玲[1] 冯景 朱俊俊 华子恺[1] ZHENG Ye;HUANG Xiuling;FENG Jing;ZHU Junjun;HUA Zikai(School of Mechatronic Engineering and Automation,Shanghai University,Shanghai 200444,China)

机构地区：[1]上海大学机电工程与自动化学院,上海200444

出　　处：《上海大学学报（自然科学版）》2023年第2期200-210,共11页Journal of Shanghai University:Natural Science Edition

基　　金：国家自然科学基金青年基金资助项目(62203287)。

摘　　要：维生素E稳定型高交联聚乙烯(vitamin E stabilized highly cross-linked polyethylene, VE/HXLPE)是一种抗氧化、低磨损的材料,该材料磨屑是否可以用现有标准方法提取还未知.基于标准,采用酸消化法降解体外磨损实验中的润滑介质,通过设置不同的消化液取样量指标,探究其对磨屑数量、体积、形貌特征的影响.结果表明,改变磨屑提取方法中的取样量会影响提取的磨屑数量、体积及形貌分布.采用现行标准提取到的磨屑VE/HXLPE较少,难以达到表征数量,而增加消化液取样量可有效改善这一问题,更适用于提取低磨损的VE/HXLPE磨屑.Vitamin E stabilized highly cross-linked polyethylene(VE/HXLPE)is a antiox-idant material with low wear,and it is unknown whether the wear debris of this material can be extracted by the existing standard methods.Based on standard,this paper used acid digestion method to degrade the calf serum protein in vitro wear test,and set different sampling volume of the digestivefluid to explore its influence on the characteristics of the wear debris.The results show that changing the sampling volume in the extraction method will affect the quantity,volume and morphology distribution of the extracted debris.The quantity of VE/HXLPE wear debris extracted by the existing standard is small,and it is diffcult to achieve the characterized quantity.Increasing the sampling volume of digestivefluid can effectively improve this problem,which is more suitable for extracting low-wear VE/HXLPE wear debris.

关 键 词：人工膝关节 维生素E稳定型高交联聚乙烯 磨屑提取 

分 类 号：R331[医药卫生—人体生理学]