Infection related membranoproliferative glomerulonephritis secondary to anaplasmosis:A case  

作　　者：Maulik K Lathiya Praveen Errabelli Salvatore Mignano Susan M Cullinan 

机构地区：[1]Department of Emergency Medicine,Mayo Clinic Health System,Eau Claire,WI 54703,United States [2]Department of Nephrology,Mayo Clinic Health System,Eau Claire,WI 54703,United States [3]Department of Pathology,Mayo Clinic,Rochester,MN 55905,United States

出　　处：《World Journal of Nephrology》2023年第3期66-72,共7页世界肾病学杂志（英文版）

摘　　要：BACKGROUND Anaplasmosis is a tick-borne disease with a range of clinical manifestations,from a flu-like illness with fever and myalgias to a severe systemic disease with multisystem organ failure.Although renal involvement is not a common presentation,there have been few cases reporting acute kidney injury from Anaplasmosis.CASE SUMMARY We present a 55-year-old female with anaplasmosis who developed acute kidney injury due to membranoproliferative glomerulonephritis(MPGN).The patient originally presented with cough and shortness of breath.She was admitted to the hospital with a diagnosis of community acquired pneumonia and received antibiotics.During the hospital course she developed severe acute renal failure.Initial serological work up didn’t provide any conclusive diagnosis.Hence,she underwent kidney biopsy which showed MPGN pattern suggesting autoimmune,multiple myeloma or infectious etiology.Extensive work up was undertaken which was negative for autoimmune diseases,vasculitis panel,paraproteinemias but tested positive for IgG anaplasma with high titers indicating Anaplasmosis.CONCLUSION Our case shows a unique presentation of severe acute renal failure from MPGN from tick borne illness.MPGN is usually seen with autoimmune diseases,hepatitis C virus infections,paraproteinemias.Hence,we suggest that tick borne illness should also be considered when evaluating acute renal failure cases in tick borne prevalent regions.

关 键 词：Acute kidney injury Membranoproliferative glomerulonephritis TICK-BORNE ANAPLASMOSIS Case report 

分 类 号：R69[医药卫生—泌尿科学]