桫椤的化学成分及药理活性研究进展  

Research Progress on Chemical Components and Pharmacological Activities of Alsophila Spinulosa

作　　者：王文沛 张昊祯 Ishaq Muhammad 徐宇 吴嘉佳 罗巍 李莎莎 肖雪 严诗楷[1,4] 金慧子 WANG Wen-pei;ZHANG Hao-zhen;ISHAQ Muhammad;XU Yu;WU Jia-jia;LUO Wei;LI Sha-sha;XIAO Xue;YAN Shi-kai;JIN Hui-zi(School of Pharmacy,Shanghai Jiao Tong University,Shanghai 200240,China;NMPA Key Laboratory for Rapid Testing Technology of Drugs,Guangdong Institute for Drug Control,Guangzhou 510663,China;The Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine,Guangzhou 510006,China;Institute of Chinese Medicinal Sciences,Guangdong Pharmaceutical University,Guangzhou 510006,China)

机构地区：[1]上海交通大学药学院,上海200240 [2]国家药品监督管理局,药品快速检验技术重点实验室(广东省药品检验所),广东广州510663 [3]广州中医药大学第二附属医院,广东广州510006 [4]广东药科大学中医药研究院,广东广州510006

出　　处：《化学试剂》2023年第6期44-51,共8页Chemical Reagents

基　　金：国家药品监督管理局快速检验技术重点实验室开放课题项目(KF2022002,KF2022006)。

摘　　要：桫椤(Alsophila spinulosa)是一种木本蕨类植物,是我国重要的药食同源品种。其主要成分有黄酮、甾体、三萜类化合物、苯丙素类、芳香族、有机酸、脑苷脂类、脂肪烃等。通过对桫椤提取物及其活性成分的药理作用进行总结,发现其具有抗菌、镇痛、抗氧化、祛痰止咳、免疫调节、抗肿瘤以及抗阿尔兹海默等生物活性。基于近年来公开发表的文献,对桫椤的化学成分、主要药理作用进行综合分析,并对临床应用现状进行整理和总结,旨在为桫椤的深入研究和开发利用提供参考。Alsophila spinulosa is a kind of woody fern.It is an important medicinal and edible homologous species in China.Its main components are flavonoids,steroids,triterpenoids,phenylpropanoids,aromatic,organic acids,cerebral glycosides,aliphatic hydrocarbons and so on.By summarizing the pharmacological effects of Alsophila spinulosa extract and its active components,it was found that it has biological activities such as antibacterial,analgesic,antioxidation,expectorant and cough relieving,immune regulation,anti-tumor and anti-Alzheimer.Based on the published literatures in recent years,the chemical components and main pharmacological effects of Alsophila spinulosa were comprehensively analyzed,and the current situation of clinical application was sorted out and summarized,aiming to provide reference for the in-depth research,development and utilization of Alsophila spinulosa.

关 键 词：桫椤 化学成分 抗菌 镇痛 抗氧化 祛痰止咳 抗肿瘤 免疫调节 

分 类 号：TB34[一般工业技术—材料科学与工程]