碳纳米管原生手性电化学传感器应用研究进展  

Research Progress in Electrochemical Sensors Application of Inherent Chirality of Carbon Nanotubes

作　　者：旷文祝 杨洋 罗红霞[1] 朱志伟[2] KUANG Wen-zhu;YANG Yang;LUO Hong-xia;ZHU Zhi-wei(Department of Chemistry,School of Science,Renmin University of China,Beijing 100872,China;College of Chemistry and Molecular Engineering,Peking University,Beijing 100871,China)

机构地区：[1]中国人民大学理学院化学系,北京100872 [2]北京大学化学与分子工程学院,北京100871

出　　处：《化学试剂》2023年第6期69-77,共9页Chemical Reagents

基　　金：国家自然科学基金资助项目(21775007)。

摘　　要：手性是自然界中广泛存在的现象。通常情况下,对映异构体在生物体内有着不尽相同、甚至完全相反的代谢、毒理及药理学特性。因此,研究简单高效、快速灵敏的手性识别方法,在分析化学、生物医学、药学等领域都有着非常重要的意义。然而,对映异构体有着几乎完全相同的理化性质,这导致它们的选择性识别异常困难。近年来,由于碳纳米管(CNTs)独特的原生手性,使其在对映异构体的识别中展现出卓越性质,为手性电化学传感器的研究开拓了新路径。目前利用CNTs原生手性作为识别材料的电化学传感器的综述未见报道。详细总结了近十年来CNTs原生手性电化学传感器的研究进展,包括其构建方法、识别机理以及相关应用。最后,讨论了该领域现存的挑战,展望了其未来的发展前景。Chirality is a widespread phenomenon in nature.Enantiomers basically exhibit different or even entirely opposite metabolic,toxicological and pharmacological properties in organisms,and therefore the development of simple,rapid and effective methods for chirality recognition is significant in the fields of analytical chemistry,biomedicines,pharmaceutics,and so on.However,enantiomers have almost identical physical and chemical properties,which make their selective discrimination extremely difficult.Owing to the unique “inherent chirality” of carbon nanotubes,they have been shown excellent properties in enantiomers discrimination,paving a new way for the research of chiral electrochemical sensors.However,there are no reviews focused on this point.In this review,the research progress on inherent chirality of CNTs-based electrochemical sensors in the past ten years was summarized in detail,including their construction methods,recognition mechanism and related applications.Finally,the challenges and prospects in this field were as well discussed.

关 键 词：手性 手性识别 电化学传感 碳纳米管 原生手性 

分 类 号：O657.1[理学—分析化学]