重视严重烧伤后期并发持续炎症-免疫抑制-分解代谢综合征  

Pay attention to persistent inflammation-immunosuppression-catabolism syndrome in the late stage of severe burns

作　　者：李孝建 汤文彬 Li Xiaojian;Tang Wenbin(Department of Burns and Plastic Surgery,Guangzhou Red Cross Hospital of Jinan University,Guangzhou 510220,China)

机构地区：[1]暨南大学附属广州红十字会医院烧伤整形科,广州510220

出　　处：《中华烧伤与创面修复杂志》2023年第5期407-410,共4页Chinese Journal of Burns And Wounds

基　　金：广州市科技计划项目(202102010058);广州市医学重点学科;广州市卫生健康科技项目一般引导项目(20221A010016);广州市科学技术局2022年基础研究计划项目-市校联合资助项目(202201020003)。

摘　　要：随着严重烧伤后脏器并发症的研究不断深入及器官功能监护和支持技术的不断提高,严重烧伤患者在早期和中后期避免了因休克、感染等导致的死亡,进入烧伤后期。其中部分患者因为烧伤创面未能及时和有效愈合,大面积烧伤创面长时间暴露以及感染等,处于发热、消瘦和创面迁延不愈等慢性危重症状态并伴有免疫功能下降、贫血、低蛋白血症等,表现为持续炎症-免疫抑制-分解代谢综合征(PICS),导致住院时间延长、远期病死率升高。该文结合笔者团队烧伤救治的临床实践,对严重烧伤患者后期并发PICS的主要原因及PICS的临床特征、防治方法进行简要阐述,期望引起同行对严重烧伤后期PICS的重视.With the deepening of researches on organ complications after severe burns and the continuous improvement of monitoring and support technology for organ function,severe burn patients have avoided death in the early and middle to late stages due to shock,infection,etc.,and entered the late stage of burns.Due to the failure of timely and effective burn wound healing and long-term exposure and infection of extensive burn wounds,some of these patients were in chronic and critical conditions such as fever,emaciation,and delayed wound healing that are accompanied by decreased immune function,anemia,and hypoproteinemia,etc.It manifested as persistent inflammation-immunosuppression-catabolism syndrome(PICS),leading to prolonged hospitalization and increased long-term mortality.Based on clinical practice of the author's team in burn treatment,this paper briefly expounds the main causes,clinical characteristics,and prevention methods of PICS in the late stage of severe burns of patients,hoping to attract the attention of peers to PICS in the late stage of severe burns.

关 键 词：烧伤 创面修复 持续炎症-免疫抑制-分解代谢综合征 

分 类 号：R644[医药卫生—外科学]