基于VOSviewer与CiteSpace的肠道菌群与高脂血症相关性研究图谱分析  

Association between gut microbiota and hyperlipidemia based on VOSviewer and CiteSpace:An atlas analysis

作　　者：亓晓萌 魏希进[2] 柳泽林 袁杰[2] QI Xiao-meng;WEI Xi-jin;LIU Ze-lin;YUAN Jie(First Clinical Medical College,Shandong University of Chinese Medicine,Ji’nan,Shandong 250014,China;不详)

机构地区：[1]山东中医药大学第一临床医学院,山东济南250014 [2]山东中医药大学附属医院心血管病科,山东济南250011

出　　处：《中国微生态学杂志》2023年第4期403-409,413,共8页Chinese Journal of Microecology

基　　金：国家自然科学基金青年基金项目(81804045);齐鲁医派中医药特色技术整理推广项目。

摘　　要：目的应用VOSviewer与CiteSpace软件分析1991—2022年肠道菌群与高脂血症相关性研究的现况与热点。方法计算机检索中国知网(CNKI)、万方(Wanfang)、维普(VIP)、Web of Science(WOS)数据库1991年1月1日至2022年4月30日肠道菌群与高脂血症相关性研究的文献。应用VOSviewer 1.6.18及CiteSpace 5.8.R3软件对纳入文献的发文国家、机构、作者和本研究领域的热点和前沿方向进行统计分析。结果纳入文献共1321篇,其中中文636篇,英文685篇。纳入文献发文量呈现逐年上升趋势。中国发文量位居世界首位,高中介中心性国家主要集中在欧美地区。中国科学院为该研究领域的核心机构,其发文量及中介中心性均为世界第一。该领域中脂质代谢、益生菌、代谢综合征、obesity(肥胖)、insulin resistance(胰岛素抵抗)等成为研究的热点。关键词时间线分析发现胰岛素抵抗、益生菌、inflammation是最新的研究前沿。结论通过对肠道菌群与高脂血症相关性研究热点和新兴趋势进行可视化分析,为以后肠道菌群及高脂血症的研究提供了参考。Objective To explore the current situation and hotspots of study on the association between gut microbiota and hyperlipidemia from 1991 to 2022 by using CiteSpace and VOSviewer softwares.Methods The literatures related to studies on the association between gut microbiota and hyperlipidemia published from January 1,1991 to April 30,2022 were searched in CNKI,Wanfang,VIP and Web of Science.The bibliometric research method and VOSviewer 1.6.18 and Citespace 5.8.R3 were used to conduct statistical analysis on the included publications.Results A total of 1,321 articles were included,including 636 in Chinese and 685 in English.The number of publications in the included literatures showed an increasing trend year by year.China ranked first in the world in terms of publication volume,while the countries with high intermediary centrality mainly concentrated in Europe and the United States.The Chinese Academy of Sciences was the core institution in this field,and its publication volume and intermediary centrality ranked first in the world.In this field,lipid metabolism,probiotics,metabolic syndrome,obesity and insulin resistance had become hot topics.Insulin resistance,probiotics and inflammation were the latest research frontiers.Conclusion This visual analysis of the hotspots and emerging trends of the research on the correlation between intestinal flora and hyperlipidemia may provide a reference for the future research on intestinal flora and hyperlipidemia.

关 键 词：肠道菌群 高脂血症 CITESPACE VOSviewer 文献计量学 

分 类 号：R589.2[医药卫生—内分泌]