“俞募配穴”敷贴疗法对慢性失眠患者主观睡眠、情绪和多导睡眠图的影响  

The Clinical Effect of Acupoint Application at Back-Shu and Front-Mu Points on Subjective Sleep,Emotion and Polysomnography in Patients with Chronic Insomnia

作　　者：赵娜[1] 谢晨[2] 于心同[1] 陈云飞[1] 杨文佳[1] ZHAO Na;XIE Chen;YU Xintong;CHEN Yunfei;YANG Wenjia(Yueyang Integrative Medicine Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200437,China;Shanghai Institute of Acupuncture and Meridian,Shanghai 200030,China)

机构地区：[1]上海中医药大学附属岳阳中西医结合医院,上海200437 [2]上海市针灸经络研究所,上海200030

出　　处：《中医药导报》2023年第5期80-85,98,共7页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：上海市科学技术委员会中医药科技支撑项目(144019319000);上海市科学技术委员会“科技创新行动计划”医学创新研究专项项目(20MC19200500);上海市卫生健康委员会综合医院中西医结合专项项目(ZHYY-ZXYJHZX-202018)。

摘　　要：目的:观察“俞募配穴”敷贴疗法对慢性失眠肝郁脾虚证患者睡眠量表、情绪量表和多导睡眠图(PSG)的改善作用。方法:将66例慢性失眠肝郁脾虚证患者随机分为治疗组和对照组,每组33例。治疗组取肝俞、期门、脾俞、章门给予安眠贴治疗,对照组给予安慰贴治疗。观察两组治疗前后匹兹堡睡眠质量指数量表(PSQI)、失眠严重指数量表(ISI)、贝克抑郁量表(BDI)、贝克焦虑量表(BAI)评分变化,并在治疗结束后1个月、3个月随访。治疗前后采用PSG监测患者客观睡眠情况变化。结果:治疗组总有效率为87.88%(29/33),对照组总有效率为48.48%(16/33),治疗组总有效率高于对照组,差异有统计学意义(P<0.01)。与治疗前比较,对照组患者治疗后及随访1个月ISI评分显著下降(P<0.05),治疗后BAI评分显著下降(P<0.05);治疗组患者治疗后、随访1个月、随访3个月PSQI、ISI、BDI、BAI评分均明显下降(P<0.05)。治疗组患者治疗后、随访1个月、随访3个月PSQI、ISI、BDI、BAI评分均明显低于对照组(P<0.05)。与治疗前比较,治疗组患者治疗后总睡眠时间(TST)延长,睡眠效率(SE)升高,入睡潜伏期(SOL)、入睡后清醒时间(WASO)缩短,微觉醒指数降低,差异均有统计学意义(P<0.01);对照组患者治疗后PSG各指标与治疗前比较,差异均无统计学意义(P>0.05);治疗后两组比较,治疗组患者治疗后TST、SE高于对照组,SOL、WASO低于对照组,差异均有统计学意义(P<0.01)。结论:“俞募配穴”敷贴疗法治疗慢性失眠肝郁脾虚证疗效确切,能改善患者的主观睡眠质量,调节其情绪,改善患者PSG客观睡眠指标,提高睡眠质量。Objective:To observe the clinical effect of acupoint application at Back-Shu and Front-Mu points on sleep scales,emotion scales and polysomnography(PSG)in patients with liver-stagnation and spleen-deficiency syndrome chronic insomnia.Methods:Totally 66 patients with liver-stagnation and spleen-deficiency syndrome chronic insomnia were randomly divided into treatment and control groups,33 cases in each group.The treatment group was treated by acupoint application at Ganshu(BL 18),Qimen(LR 14),Pishu(BL 20)and Zhangmen(LR 13)with Anmian Tie(安眠贴),while the control group were treated by placebo application.The change of Pittsburgh Sleep Quality Index(PSQI),Insomnia Severity Index(ISI),Beck Depression Inventory(BDI)and Beck Anxiety Inventory(BAI)were observed,and the patients were followed up 1 month and 3 months after the end of treatment.PSG was used to monitor the patients'objective sleep before and after the treatment.Results:The total effective rate was 87.88%(29/33)in treatment group and 48.48%(16/33)in control group.The treatment group showed higher total effective rate than control goup,and the difference was statistically significant(P<0.01).Compared with before treatment,the ISI score was significantly decreased in the control group after treatment and 1 month follow-up(P<0.05),and the BAI score significantly decreased in the control group after treatment.Compared with before treatment,the PSQI,ISI,BDI and BAI scores were significantly decreased in treatment group after treatment,1 month follow-up and 3 month follow-up(P<0.05).The treatment group showed lower scores of PSQI,ISI,BDI and BAI than control group after treatment,1 month and 3 months of follow-up(P<0.05).Compared with before treatment,in terms of sleep process parameters,the total sleep time(TST)and sleep efficiency(SE)increased,while sleep onset latency(SOL),awake time after sleep(WASO)and arousal awake index decreased in treatment group after the treatment(P<0.05).There was no significant difference in sleep process parameters in control gr

关 键 词：慢性失眠 肝郁脾虚证 俞募配穴 安眠贴 敷贴疗法 睡眠量表 情绪量表 多导睡眠图 临床研究 

分 类 号：R246.6[医药卫生—针灸推拿学]