急性ST段抬高型心肌梗死患者直接经皮冠状动脉介入治疗术后无复流现象的最新研究进展  

Contemporary progress of no refl ow phenomenon after primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction

作　　者：郝伟 赵晨[1] 胡思宁[1] 贾海波[1] 于波[1] HAO Wei;ZHAO Chen;HU Si-ning;JIA Hai-bo;YU Bo(Department of Cardiology,the 2nd Affi liated Hospital of Harbin Medical University,Harbin 150001,China)

机构地区：[1]哈尔滨医科大学附属第二医院心内科,黑龙江哈尔滨150001

出　　处：《中国介入心脏病学杂志》2023年第5期380-386,共7页Chinese Journal of Interventional Cardiology

基　　金：黑龙江省自然科学基金研究团队项目(TD2020H001)。

摘　　要：直接经皮冠状动脉介入治疗(PPCI)的广泛开展显著降低了急性ST段抬高型心肌梗死(STEMI)患者的死亡率。然而,有相当部分患者在冠状动脉重新开通后出现无复流(NR)现象,这严重限制了STEMI患者冠状动脉血运重建后的临床获益,并与患者的不良预后密切相关。本文主要就STEMI患者PPCI术后NR的诊断、病理机制、预测因素及其防治策略的最新研究成果及进展进行综述。The development of primary percutaneous coronary intervention(PPCI)has signifi cantly reduced mortality of patients with acute ST-segment elevation myocardial infarction(STEMI).However,a considerable number of STEMI patients may suff er from coronary no-refl ow(NR)phenomenon after revascularization,which severely restricts the clinical benefi t of coronary revascularization and is closely associated with poor prognosis in STEMI patients.This paper mainly reviews the latest research fi ndings and progress on the diagnosis,pathological mechanisms,predictors,prevention and treatment strategies of NR after PPCI in patients with STEMI.

关 键 词：急性ST段抬高型心肌梗死 经皮冠状动脉介入治疗 无复流现象 微循环阻塞 

分 类 号：R541.4[医药卫生—心血管疾病]