De novo biosynthesis of a vinblastine precursor in Pichia pastoris  

作　　者：Jiaming Yu Dongyuan Lv Lixin Zhang 

机构地区：[1]State Key Laboratory of Bioreactor Engineering,East China University of Science and Technology,Shanghai,200237,China

出　　处：《Synthetic and Systems Biotechnology》2023年第2期300-301,共2页合成和系统生物技术（英文）

摘　　要：Plant natural products have been widely used in medicine,food,and cosmetics.Of a particular note,many natural products from Cathar-anthus roseus have important biological activities and medicinal value^([1]),with vinblastine as one of the most effective drugs for cancer treatment^([2]).Due to difficulties in chemical synthesis of such complex structures,plant extraction is still the major method for large-scale preparation of plant natural products.

关 键 词：products. synthesis PREPARATION 

分 类 号：O62[理学—有机化学]