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作 者:叶学坤 YE Xuekun(Shaxian District General Hospital of Sanming City,Sanming 365500,China)
出 处:《中外医学研究》2023年第13期161-164,共4页CHINESE AND FOREIGN MEDICAL RESEARCH
摘 要:目的:分析嵌顿性输尿管结石患者实施微创经皮肾镜碎石术(MPCNL)与输尿管软镜碎石术(FURL)的效能及安全性。方法:选取三明市沙县区总医院2020年1月—2021年12月收治的82例嵌顿性输尿管结石患者为研究样本,对其进行编号,依据编号的奇偶性分为观察组和对照组,各41例。对照组行FURL,观察组行MPCNL,比较两组患者的结石清除率、围手术期指标、并发症及肾功能指标。结果:观察组术后3 d和7 d结石清除率高于对照组,差异有统计学意义(P<0.05);观察组手术时间、住院时间短于对照组,但观察组手术失血量多于对照组,差异有统计学意义(P<0.05);观察组并发症发生率显著低于对照组,差异有统计学意义(P<0.05);治疗后观察组血肌酐(Scr)、尿素氮(BUN)、β_(2)-微球蛋白(β_(2)-MG)低于对照组,差异有统计学意义(P<0.05)。结论:在嵌顿性输尿管结石的手术治疗中,MPCNL较FURL的术中失血量明显,但是手术效能更佳,且安全性更高,术后患者的肾功能恢复更快。Objective:To analyze the efficacy and safety of minimally-invasive percutaneous nephrolithotomy(MPCNL)and flexible ureteroscopic lithotripsy(FURL)in patients with incarcerated ureteral calculi.Method:A total of 82 patients with incarcerated ureteral calculi admitted to Shaxian District General Hospital of Sanming City from January 2020 to December 2021 were selected as the study subjects,and they were numbered,according to the parity of the numbers,they were divided into observation group and control group,41 cases in each group.The control group was treated with FURL,and the observation group was treated with MPCNL.The treatment results,surgical information,complications and renal function indicators of the two groups were compared.Result:The stone clearance rates of 3 d and 7 d after operation in the observation group were higher than those in the control group,the differences were statistically significant(P<0.05).The operation duration and hospitalization time in the observation group were lower than those in the control group,but the intraoperative blood loss in the observation group was higher than that in the control group,the differences were statistically significant(P<0.05).The incidence of complications in the observation group was significantly lower than that in the control group,the difference was statistically significant(P<0.05).After surgical treatment,the renal function indexes serum creatinine(Scr),urea nitrogen(BUN),β_(2)-microglobulin(β_(2)-MG)in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).Conclusion:In the surgical treatment of incarcerated ureteral calculi,the intraoperative blood loss of MPCNL was more obvious than that of FURL,but it is more effective and safe,and the renal function of patients after the operation recovers faster.
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