急性肾损伤早期生物标志物的研究进展  

Progress of research on early biomarkers of acute kidney injury

作　　者：任涛涛 乔晞[1] Ren Taotao;Qiao Xi(Department of Nephrology,Second Hospital of Shanxi Medical University,Shanxi Provincial Institute for Kidney Disease,Kidney Disease Institute of Shanxi Medical University,Taiyuan 030001,Shanxi Province,China)

机构地区：[1]山西医科大学第二医院肾内科、山西省肾脏病研究所、山西医科大学肾病研究所,太原030001

出　　处：《中华肾病研究电子杂志》2023年第1期32-38,共7页Chinese Journal of Kidney Disease Investigation（Electronic Edition）

基　　金：山西省回国留学人员科研资助项目(2020-186);山西省留学回国人员科技活动择优资助项目(2017-29)。

摘　　要：急性肾损伤(AKI)是危重患者常见的并发症之一,发病率和死亡率居高不下,严重影响患者预后,早期诊断及干预尤为关键。目前诊断AKI所依赖的血清肌酐和尿量指标有一定局限性,寻找有效的早期生物标志物已经成为AKI研究的当务之急。近年来不断有新的研究成果问世,本文综述了有关AKI早期诊断生物标志物的最新研究进展。Acute kidney injury(AKI)is one of the common complications in critically ill patients.The incidence and mortality of AKI are high,which seriously affects the prognosis of patients.Early diagnosis and intervention are particularly important.At present,the indexes of serum creatinine and urine volume on which the diagnosis of AKI depends have certain limitations,and finding effective early biomarkers has become the urgent task of AKI research.In recent years,new research results have been published continually.This article reviewed the latest progress of research on early biomarkers of AKI diagnosis.

关 键 词：急性肾损伤 早期诊断 标志物 

分 类 号：R692[医药卫生—泌尿科学]