机构地区:[1]江西中医药大学附属医院妇科,江西南昌330000
出 处:《实用妇科内分泌电子杂志》2022年第36期27-29,33,共4页Electronic Journal of Practical Gynecological Endocrinology
基 金:江西省中医药科技计划一般项目(编号2020A0217)。
摘 要:目的 探讨在红外热断层扫描(TTM)技术指导下采用热敏灸联合穴位贴敷治疗卵泡发育不良性不孕症的效果。方法 选择75例卵泡发育不良性不孕症患者为研究对象,按照随机数字表法随机分为三组,每组25例。观察组采用TTM+热敏灸+穴位贴敷疗法,对照A组采用热敏灸+穴位贴敷疗法,对照B组采用口服克罗米芬+人绒毛膜促性腺激素(HCG)法。比较三组卵泡成熟情况、内膜厚度、三线征阳性、子宫动脉阻力指数(RI)值、性激素水平、中医体质评分等。结果 观察组妊娠率为48%,高于对照A组的36%及对照B组的12%(P<0.05)。治疗后,观察组优势卵泡率、卵泡成熟数、内膜厚度及三线征阳性率均优于对照A组、对照B组(P<0.05),三组卵泡成熟天数、RI值比较差异无统计学意义(P>0.05);治疗前,三组的性激素指标及抗苗勒管激素(AMH)比较,差异均无统计学意义(P>0.05);治疗后三组促黄体生成素(LH)卵泡刺激素(FSH)、雌二醇(E_(2))、孕酮(P)、睾酮(T)、泌乳素(PRL)及AMH水平均有所改善,而观察组改善优于对照A组、对照B组(P<0.05),治疗前,三组中医体质评分比较,差异均无统计学意义(P>0.05);治疗后,观察组、对照A组阳虚体质评分低于治疗前(P<0.05),且低于对照B组(P<0.05)。结论 在TTM技术指导下采用热敏灸联合穴位贴敷可促进卵泡发育及内膜生长,改善临床症状及生殖内分泌水平,从而提高疗效。Objective To investigate the effect of heat-sensitive moxibustion combined with acupoint application on infertility caused by follicular dysplasia under the guidance of infrared thermal tomography(TTM) technology.Methods Seventy-five infertility patients with follicular dysplasia were randomly divided into three groups with 25 patients in each group according to the random number table method.TTM+ heat-sensitive moxibustion + acupoint application therapy was used in the observation group,heat-sensitive moxibustion + acupoint application therapy was used in the control group A,and oral clomiphene + human chorionic gonadotropin(HCG)method was used in the control group B.Follicle maturation,endometrial thickness,positive three-line signs,uterine artery resistance index(RI) value,sex hormone level,traditional Chinese medicine physique score and so on were compared among the three groups.Results The pregnancy rate in the observation group was 48%,which was higher than that in control group A(36%) and control group B(12%)(P<0.05).After treatment,the dominant follicle rate,number of follicle maturation,endometrium thickness and positive rate of three-line sign in the observation group were better than those in control group A and control group B(P<0.05).There were no significant differences in follicle maturation days and RI value among the three groups(P>0.05).Before treatment,there were no significant differences in therapeutic sex hormone indexes and antimullerian hormone(AMH) among the three groups(P>0.05).After treatment,the levels of luteinizing hormone(LH) follicle stimulating hormone(FSH),estradiol(E_2),progesterone(P),testosterone(T),prolactin(PRL) and AMH in the three groups were improved,and the improvement in the observation group was better than that in control group A and control group B(P<0.05).Before treatment,there was no statistical significance in TCM physique scores among the three groups(P>0.05).After treatment,Yang deficiency constitution scores of observation group and control group A were lower t
关 键 词:卵泡发育不良性不孕症 热敏灸 穴位贴敷 TTM技术
分 类 号:R246.3[医药卫生—针灸推拿学]
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