锁孔开颅微血管减压术治疗前庭阵发症的初步研究  

Preliminary study of keyhole craniotomy for microvascular decompression in the treatment of vestibular paroxysmia

作　　者：王永楠[1] 王启弘 殷杰[1] 欧春影[2] Yongnan Wang;Qihong Wang;Jie Yin;Chunying Ou(Department of Neurosurgery,Xuzhou Central Hospital(Xuzhou School of Clinical Medicine of Nanjing Medical University),Xuzhou 221000,China;Department of Neurology,Xuzhou Central Hospital(Xuzhou School of Clinical Medicine of Nanjing Medical University),Xuzhou 221000,China)

机构地区：[1]徐州市中心医院(南京医科大学徐州临床医学院)神经外科,221000 [2]徐州市中心医院(南京医科大学徐州临床医学院)神经内科,221000

出　　处：《中华神经创伤外科电子杂志》2023年第1期43-47,共5页Chinese Journal Of Neurotraumatic Surgery：Electronic Edition

基　　金：江苏省科技厅临床医学专项课题(BL2014028)。

摘　　要：目的:探讨前庭蜗神经微血管减压术(MVD)治疗前庭阵发症(VP)的疗效。方法:选取徐州市中心医院神经外科自2016年6月至2022年10月收治的10例明确诊断为VP的患者,均全麻下行乙状窦后锁孔入路前庭蜗神经MVD,随访10~30个月,观察手术治疗效果。结果:10例患者手术中均探及微血管压迫前庭蜗神经。术后5例患者症状立即消失,3例患者症状较术前减轻,其中2例患者随访12个月后症状逐步减轻至消失;2例患者术后症状无明显改善,其中1例患者随访20个月后症状改善。所有患者未见不良反应。结论:在严格把握手术适应证的前提下,前庭蜗神经的MVD手术可成为治疗VP安全有效的选择。Objective To investigate the efficacy of microvascular decompression (MVD) of vestibulocochlear nerve for treatment of vestibular paroxysmia (VP).MethodsTen patients admitted by Neurosurgery Department of Xuzhou Central Hospital from June 2016 to October 2022 were diagnosed as VP. MVD of vestibulocochlear nerve through retrosigmoid approach under general anesthesia was performed on those 10 patients, all of whom were followed up for 10-30 months to evaluate the treatment outcome.ResultsMicrovascular compression of vestibulocochlear nerve was found in all 10 patients during operation. After operation, 5 patients were cured and 3 patients were improved, of which 2 patients gradually relieved to disappear after 12 months of follow-up, 2 patients had no obvious improvement in postoperative symptoms, of which 1 patient improved after 20 months of follow-up. No adverse reactions were found in all patients.ConclusionUnder the premise of strict sugical indications, vestibulocochlear neurovascular decompression can be a safe and effective choice for treating vestibular paroxysmal disease.

关 键 词：前庭阵发症 微血管减压术 血管神经压迫 

分 类 号：R651.1[医药卫生—外科学]