脓毒性心肌病增加脓毒症患者的全因院内病死率  

Septic cardiomyopathy increases all-cause in-hospital mortality of patients with sepsis

作　　者：孙蒙奇 姚续[1] 王辉 鹿辉 李涛[2] 张灯亮[1] SUN Meng-qi;YAO Xu;WANG Hui(Intensive Care Unit,People Hospital of Taihe County,Anhui 236699,China)

机构地区：[1]太和县人民医院重症医学科,安徽阜阳236600 [2]中日友好医院重症医学科,北京100029

出　　处：《中日友好医院学报》2023年第2期81-84,102,共5页Journal of China-Japan Friendship Hospital

基　　金：国家高水平医院临床研究项目(2022-NHLHCRF-LX-02-0124)。

摘　　要：目的:评估脓毒性心肌病是否与脓毒症患者的全因院内病死率相关。方法:回顾分析2019年9月—2022年9月太和县人民医院重症医学科收治的脓毒症患者181例,根据是否发生脓毒性心肌病,分为脓毒性心肌病组和非脓毒性心肌病组。收集患者的临床数据,对比分析2组患者病死率的差异,并应用Logistic回归分析影响预后的危险因素。结果:181例患者中脓毒性心肌病组32例,非脓毒性心肌病组149例。脓毒性心肌病组病死率(53.1%)显著高于非脓毒性心肌病组(8.72%),差异有统计学意义(P<0.05)。脓毒性心肌病、动脉血乳酸、腹腔感染源、病原菌培养阳性、APACHEⅡ评分(OR=5.57、1.63、1.92、1.65、1.47,均P<0.05)是脓毒症患者院内全因病死率的独立预测因素。结论:脓毒性心肌病增加脓毒症患者院内全因病死率。Objective:To assess whether septic cardiomyopathy is associated with all-cause in-hospital mortality of patients with sepsis.Methods:The data of patients with sepsis who were admitted to our hospital from September 2019 to September 2022 were summarized retrospectively.Patients who met the inclusion criteria would be classified into the septic and non-septic cardiomyopathy groups based on whether or not developing septic cardiomyopathy.The all-cause in-hospital mortality between the two groups were compared,and logistic regression was performed to evaluate predictors of mortality.Results:Among 181 enrolled patients in the study,32 patients were in septic cardiomyopathy group,with all-cause in-hospital mortality of 53.1%,which was significantly higher than that in the non-septic cardiomyopathy group(8.72%,P<0.05).Septic cardiomyopathy was an independent risk factor of all-cause in-hospital mortality among sepsis patients(OR=5.57,95%CI 2.96~10.73,P<0.05).Conclusion:Septic cardiomyopathy increases all-cause in-hospital mortality of patients with sepsis.

关 键 词：脓毒性心肌病 脓毒症 院内全因病死率 

分 类 号：R542.2[医药卫生—心血管疾病]