选择适宜治疗方案正确评估抗结核治疗疗效提高利福平敏感结核病治疗质量  

Select appropriate treatment plan and correctly evaluate the efficacy of anti-tuberculosis treatment,improving the treatment quality of rifampicin sensitive tuberculosis

作　　者：周林[1] 刘二勇[1] 赵雁林[1] Zhou Lin;Liu Eryong;Zhao Yanlin(National Center for Tuberculosis Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China)

机构地区：[1]中国疾病预防控制中心结核病预防控制中心,北京102206

出　　处：《结核与肺部疾病杂志》2023年第3期189-193,共5页Journal of Tuberculosis and Lung Disease

基　　金：232811结核业务日常运转。

摘　　要：规范利福平敏感结核病的治疗,提高治疗质量,无论是对耐药结核病防治,还是控制结核病流行都至关重要。首先,重视病原学检查,结合结核病患者病情选择适宜辅助检查,按照结核病病变类型使用对应治疗方案;第二,首选一线抗结核药品,无胃肠道吸收功能障碍患者,全疗程口服用药;第三,使用标准抗结核治疗方案,即强化期使用H-R-Z-E治疗方案,足量用药,利福平敏感结核病抗结核治疗推荐使用抗结核固定剂量复合制剂(FDC);第四,病原学检查是判断抗结核治疗疗效的金标准,客观评价患者治疗疗效,完成抗结核治疗疗程,符合治疗成功条件的患者可以停止抗结核治疗。Regulating the treatment of rifampicin-sensitive tuberculosis and improving the quality of treatment are crucial for the prevention and treatment of drug-resistant tuberculosis and the control of the tuberculosis epidemic.First of all,attach importance to etiological examination,choose suitable auxiliary examination in combination with the condition of tuberculosis patients,and use the corresponding treatment plan according to the type of tuberculosis;second,first-line anti-tuberculosis drugs are preferred,patients without gastrointestinal absorption dysfunction should take oral drugs for the whole course of treatment;third,use standard anti-tuberculosis treatment plan,that is,using H-R-Z-E in the intensive period and taking sufficiently,it is recommended to use anti-tuberculosis fixed-dose combination(FDC)for anti-tuberculosis treatment;fourth,etiological examination is the gold standard for judging the efficacy of anti-tuberculosis treatment,objectively evaluating the therapeutic effect of patients.The patients who completing the course of anti-tuberculosis treatment and meeting with the treatment success standard,can stop anti-tuberculous treatment.

关 键 词：结核 方案评价 抗结核药 治疗结果 

分 类 号：R52[医药卫生—内科学]