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作 者:芦雨 王晓东[1] Lu Yu;Wang Xiaodong(Respiratory Department,The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)
机构地区:[1]郑州大学第一附属医院呼吸内科,郑州450052
出 处:《结核与肺部疾病杂志》2023年第3期240-245,共6页Journal of Tuberculosis and Lung Disease
基 金:河南省医学科技攻关省部共建重点项目(SBGJ202102090)。
摘 要:慢性阻塞性肺疾病(简称“慢阻肺”)相关性疲劳是慢阻肺患者中发生率仅次于呼吸困难的第二大症状。该症状的存在不仅限制患者的日常活动,影响社交,带来负性情绪甚至与急性加重、预后恶化、死亡率增加等具有独特相关性。药物治疗虽能在一定程度上改善疲劳,但作用有限,周期、规律的非药物干预是缓解疲劳的关键。但当前国内研究人员对此关注尚不足,相关干预研究也较少。因此,本文从慢性阻塞性肺疾病相关性疲劳的概念、发生机制及非药物干预措施进行更新和综述,以期为国内临床工作及研究的开展提供参考。Second to dyspnea,chronic obstructive pulmonary disease(COPD)-related fatigue is the second common symptom COPD patients with.The symptom not only restricts patients’daily activities,affects social interaction,brings negative emotions,but also has a unique correlation with acute exacerbation,worsening prognosis and increased mortality.Although drug therapy can improve fatigue to some extent,its effect is limited.Periodic and regular non-drug intervention is the key to relieve fatigue.However,at present,domestic attention is not enough,and the amount of related intervention studies is also small.Therefore,this paper updates and reviews the concept,pathogenesis and non-drug intervention measures of COPD-related fatigue,in order to provide reference for clinical work and research in China.
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