3种自动勾画软件对鼻咽癌危及器官勾画结果的对比分析  

Comparative Analysis of Three Types of Softwares for Auto-Segmentation of Organs at Risk in the Nasopharyngeal Carcinoma

作　　者：马阿敏 钟毓 贺威 陈磊 王顺兰[2] 崔瑞瑞 MA Amin;ZHONG Yu;HE Wei;CHEN Lei;WANG Shunlan;CUI Ruirui(Department of Radiotherapy,The First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou Guangdong 510405,China;Department of Otolaryngology,The First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou Guangdong 510405,China;Guangzhou Ping’an Haoyi Medical Image Diagnostic Center,Guangzhou Guangdong 510030,China)

机构地区：[1]广州中医药大学第一附属医院放射治疗科,广东广州510405 [2]广州中医药大学第一附属医院耳鼻喉科,广东广州510405 [3]广州平安好医医学影像诊断中心,广东广州510030

出　　处：《中国医疗设备》2023年第6期72-76,119,共6页China Medical Devices

基　　金：国家自然科学基金面上项目(82071024)。

摘　　要：目的分析AccuContour、rtStation和PV-iCurve3种自动勾画软件勾画鼻咽癌危及器官的效果。方法随机选取广州中医药大学第一附属医院收治的30例鼻咽癌患者,由同一位医师人工勾画危及器官,分别使用3种软件进行自动勾画,以人工勾画结果为“金标准”,分别计算3种软件勾画结果的Dice相似性系数(Dice Similarity Coefficient,DSC)和Hausdorff距离(Hausdorff Distance,HD),比较3种软件勾画鼻咽癌危及器官的精确度。结果对于选取的14个危及器官,3种软件自动勾画的大部分器官的DSC均大于0.7,在视交叉和口腔这两个器官,rtStation勾画效果最优;对于其他器官的勾画,AccuContour则具有明显优势。rtStation与PV-iCurve相比,除脊髓和视交叉两个器官,rtStation均优于PV-iCurve,差异有统计学意义(P<0.05)。AccuContour与rtStation的勾画结果相比,AccuContour左眼球、左晶体、左视神经、脊髓和左颞叶这5个器官的HD均显著小于rtStation(P<0.05);对于视交叉和口腔,rtStation的勾画效果显著优于AccuContour(P<0.05)。AccuContour与PV-iCurve相比,AccuContour仅视交叉和口腔中HD大于PV-iCurve,其他12个器官,AccuContour的HD均小于PV-iCurve;rtStation和PV-iCurve相比,rtStation的HD均小于PV-iCurve,且除视交叉器官,其他13个器官两个软件比较差异均有统计学意义(P<0.05)。结论3种自动勾画软件各有优势,但在临床实际应用中,AccuContour在整体的勾画结果中效果最好,其次为rtStation。Objective To analyze the accuracy of three types of softwares:AccuContour,rtStation and PV-iCurve for the autosegmentation of organs at risk in the nasopharyngeal carcinoma.Methods A total of 30 patients with nasopharyngeal carcinoma were randomly selected from the First Affiliated Hospital of Guangzhou University of Chinese Medicine.The organs at risk were manually segmented by the same doctor firstly,then three types of softwares were used for automatic segmentation.Taking manual segmentation as the“gold standard”,the Dice similarity coefficient(DSC)and Hausdorff distance(HD)were calculated,the accuracy of three softwares in delineation of organs at risk of nasopharyngeal carcinoma were compared.Results For the selected 14 organs at risk,the DSC of most organs automatically segmented by three softwares were greater than 0.7.In the optic chiasma and oral cavity,the segmentation of rtStation was the best.AccuContour had obvious advantage in other organs.Compared with PV-iCurve,rtStation was superior to PV-iCurve in all organs at risk except spinal cord and optic chiasm and had statistically significant differences(P<0.05).Compared with the contour results of rtStation,the HD of AccuContour left ophthalm osphere,left crystal,left optic nerve,spinal cord and left temporal lobe were significantly lower than those of rtStation(P<0.05).For optic chiasma and oral cavity,rtStation was significantly better than AccuContour(P<0.05).Compared with PV-iCurve,the HD of AccuContour was higher than PV-iCurve only in the optic chiasma and oral region,and the HD of AccuContour was lower than PV-iCurve in all other 12 organs.Compared with PV-iCurve,the HD of rtStation was lower than that of PV-iCurve,and except for the optic chiasma organ,the difference between the other 13 organs were statistically significant(P<0.05).Conclusion Each of the three automatic segmentation software has its own advantages,but in clinical practice AccuContour was the most effective in overall contouring results,followed by rtStation.

关 键 词：鼻咽癌 自动勾画 危及器官 AccuContour rtStation PV-iCurve 

分 类 号：R197.39[医药卫生—卫生事业管理]