乙型肝炎病毒标志物临床应用专家共识  

Expert consensus on the clinical application of the markers of hepatitis B virus

作　　者：中华医学会肝病学分会基础医学与实验诊断协作组 陈红松[2] 鲁凤民[3] 南月敏[4] 杨瑞锋[5] 廖昊 于广鑫 陆海英[8] 赵素贤 刘灿[10] 戴二黑[11] 欧启水[10] 饶慧瑛[5] 徐小元[8] Cooperative Group of Basic Research and Experimental Diagnosis of Liver Diseases,Chinese Society of Hepatology,Chinese Medical Association;Chen Hongsong;Lu Fengmin;Nan Yuemin(不详;Peking University People's Hospital,Peking University Hepatology Institute,Beijing Key Laboratory of Hepatitis C and Immunotherapy for Liver Diseases,Bejing International Cooperation Base for Science and Technology on NAFLD Diagnosis,Beijing 100044,China;Department of Microbiology&Infectious Disease Center,Peking University Health Science Center,Beijing 100191,China;Department of Traditional and Western Medical Hepatology,Third Hospital of Hebei Medical University,Shijiazhuang 050051,China)

机构地区：[1]不详 [2]北京大学人民医院、北京大学肝病研究所丙型肝炎和肝病免疫治疗北京市重点实验室、非酒精性脂肪性肝病诊断北京市国际科技合作基地,北京100044 [3]北京大学基础医学院病原生物学系暨感染病研究中心,北京100191 [4]河北医科大学第三医院中西医结合肝病科,石家庄050051 [5]北京大学人民医院 [6]深圳市第三人民医院,国家感染性疾病临床医学研究中心 [7]北京大学基础医学院病原生物学系,北京大学感染病研究中心 [8]北京大学第一医院 [9]河北医科大学第三医院 [10]福建医科大学附属第一医院 [11]石家庄市第五医院

出　　处：《中华肝脏病杂志》2023年第4期389-400,共12页Chinese Journal of Hepatology

摘　　要：临床实践中,乙型肝炎病毒标志物主要用于诊断感染、监测疾病进展、评估慢性乙型肝炎治疗应答,以及在临床试验中评估新型抗病毒药物的疗效。结合近年来慢性乙型肝炎抗病毒治疗的研究进展和临床诊治实际需求,中华医学会肝病学分会基础医学与实验诊断协作组制订此专家共识,对经典及新型乙型肝炎病毒实验室检测相关标志物的临床应用进行证据总结和要点推荐,旨在指导其规范、合理的临床应用。Hepatitis B virus biomarkers are mainly used in clinical practice to diagnose infection,monitor disease progression,evaluate response to chronic hepatitis B treatment,and evaluate the efficacy of novel antiviral drugs in clinical trials.In combination with the recent research progress of antiviral therapy for chronic hepatitis B and the actual needs of clinical diagnosis and treatment,the expert consensus was formulated by the Cooperative Group of Basic Research and Experimental Diagnosis of Liver Diseases,Chinese Society of Hepatology,Chinese Medical Association.It summarized the evidence and recommended the key points for the clinical application of classic and novel hepatitis B virus related biomarkers in order to guide the standardized and reasonable clinical application for these biomarkers.

关 键 词：慢性乙型肝炎 诊断 治疗 标志物 

分 类 号：R512.62[医药卫生—内科学]