紫外/亚硫酸盐体系高效降解磷酸氯喹  

Efficient Degradation of Chloroquine Phosphate in the UV/Sulfite System

作　　者：顾玉蓉 赵倩雯 董紫君 黄欣颖 GU Yurong;ZHAO Qianwen;DIONG Zijun;HUANG Xinying(School of Material and Environmental Engineering,Shenzhen Polytechnic,Shenzhen 518055,China;School of Civil and Traffic Engineering,Shenzhen University,Shenzhen 518048,China)

机构地区：[1]深圳职业技术学院材料与环境工程学院,广东深圳518055 [2]深圳大学土木与交通学院,广东深圳518048

出　　处：《环境科学与技术》2023年第4期152-157,175,共7页Environmental Science & Technology

基　　金：国家自然科学基金(42107396,42277373);深圳市科技计划(JCYJ20220531094416037);深圳市科技创新委可持续发展专项(KCXFZ20201221173413037);广东省攀登计划(pdjh2022b0977)。

摘　　要：磷酸氯喹(CQP)作为有效应对新冠肺炎的药物之一,正在越来越多地被应用。CQP大量生产和使用的同时,也带来了一定的水生态安全隐患。该文考察了紫外/亚硫酸盐体系对CQP的降解效能,探究了典型水质参数对体系降解CQP的影响规律,并借助降解产物分析推断了CQP的降解路径。结果表明:紫外/亚硫酸盐体系可以高效降解CQP,初始浓度为10 mg/L的CQP经紫外光照45 s,降解率可达到100%,表观速率常数为0.1657 s^(-1)。紫外光强、亚硫酸盐投量及溶液pH的提高有助于反应体系对CQP的处理效果,而天然有机物的存在会抑制CQP的降解。CQP在紫外/亚硫酸盐体系中主要存在2条降解路径,均为侧链的取代反应。As an effective medicine for treating Covid-19,chloroquine phosphate(CQP)has been widely used recently.Along with the extensive production and use of CQP,there may bring about some threat to water security.This study investigated CQP degradation efficiency by the UV/sulfite system.Effects of typical water quality parameters on CQP degradation in the studied system were also monitored.Besides,CQP degradation pathway was elucidated based on the analysis of degradation intermediates.The results showed that high degradation efficiency was obtained in the UV/sulfite system.Complete CQP degradation was achieved after 45 s irradiation at initial CQP concentration of 10 mg/L.The observed rate constant of CQP degradation was 0.1657 s^(-1).The increase of UV intensity,sulfite dosage and solution pH was beneficial for improving CQP removal ratio in the investigated system,whereas the co-existence of NOM suppressed CQP removal to certain extent.There were two main CQP degradation pathways in the UV/sulfite system,which were both substituted reactions occurred in the side chain of CQP molecule.

关 键 词：磷酸氯喹 紫外 亚硫酸盐 抗病毒药物 水合电子 

分 类 号：X787[环境科学与工程—环境工程]