基于不同腹膜透析模式对终末期肾病患者钙磷代谢的改变研究  

Study on the Changes of Calcium and Phosphorus Metabolism in Patients with End-stage Renal Disease Based on Different Peritoneal Dialysis Modes

作　　者：李强 冯威 关金 鄂洋 蔡菁菁 LI Qiang;FENG Wei;GUAN Jin;E Yang;CAI Jingjing(Department of Nephrology,Fukuang General Hospital,Liaoning Health Industry Group,Fushun 113008,China)

机构地区：[1]辽宁省健康产业集团抚矿总医院肾内科,辽宁抚顺113008

出　　处：《中国医药指南》2023年第17期98-100,共3页Guide of China Medicine

摘　　要：目的研究不同腹膜透析模式的效果。方法本研究纳入我院2018年3月至2020年3月收治的200例终末期肾脏病患者作为研究对象,随机分为两组,即观察组和对照组各100例,分别采取经典持续非卧床腹膜透析、日间非卧床腹膜透析,分析且对比两组各项指标。结果治疗前,观察组和对照组的各项指标均差异无统计学意义(P>0.05);治疗后,观察组BUN(13.31±3.41)mmol/L、SCr指标(457.26±173.11)μmol/L低于对照组(P<0.05);观察组血钙(1.29±0.51)mmol/L、血磷指标(1.19±0.42)mmol/L低于对照组(P<0.05);观察组不良反应发生率2.00%(其中低蛋白血症1例、心力衰竭1例)低于对照组(P<0.05);观察组TNF-α、IL-6指标低于对照组(P<0.05)。结论通过对终末期肾病患者实施经典持续非卧床腹膜透析可取得显著的效果,纠正患者钙磷代谢紊乱。Objective To study the effect of different peritoneal dialysis modes.Methods A total of 200 patients with end-stage renal disease admitted to our hospital from March 2018 to March 2020 were included in this study.They were randomly divided into two groups,namely the observation group and the control group,with 100 patients in each group,classic continuous ambulatory peritoneal dialysis and daytime ambulatory peritoneal dialysis were used respectively,and the indexes of the two groups were analyzed and compared.Results Before treatment,there was no significant difference between the observation group and the control group(P>0.05).After treatment,BUN(13.31±3.41)mmol/L and SCr index(457.26±173.11)μmol/L in the observation group were lower than those in the control group(P<0.05).The blood calcium(1.29±0.51)mmol/L and blood phosphorus index(1.19±0.42)mmol/L in the observation group were lower than those in the control group(P<0.05).The incidence of adverse reactions in the observation group was 2.00%(including 1 case of hypoproteinemia and 1 case of heart failure)lower than that in the control group(P<0.05).The indexes of TNF-αand IL-6 in the observation group were lower than those in the control group(P<0.05).Conclusion Classic continuous ambulatory peritoneal dialysis for patients with end-stage renal disease can achieve significant results and correct the disorder of calcium and phosphorus metabolism.

关 键 词：终末期肾病 腹膜透析 钙磷代谢 

分 类 号：R692[医药卫生—泌尿科学]