出 处:《中国医药指南》2023年第17期117-119,135,共4页Guide of China Medicine
摘 要:目的探讨腹腔镜辅助全胃切除术与传统手术治疗对胃癌患者日常生活能力及复发率的影响。方法选取2017年1月至2019年12月我院收治的60例胃癌患者为研究对象,按照治疗方法的不同分为(腔镜组,30例)和传统组(传统组,30例),传统组患者采用传统手术治疗,腔镜组患者的手术方式为腹腔镜辅助全胃切除术。比较两组患者治疗前后日常生活活动能力(ADL)评分、各项手术指标(包括手术时间、肛门排气时间、术中出血量、住院时间)、血清学指标(包括CEA、CA199、CA125)改善情况、并发症发生率(包括肺部感染、吻合口狭窄、肠梗阻、切口感染、腹腔感染、皮下气肿)及3年复发率。结果两组患者术前CEA、CA199、CA125等血清学指标和ADL评分相比差异无统计学意义(P>0.05),术后各项血清学指标和ADL评分均显著改善(P<0.05),且腔镜组CEA、CA199、CA125等血清学指标和ADL评分改善情况显著优于传统组(P<0.05);腔镜组胃癌手术者肛门排气时间、住院时间明显短于传统组胃癌手术者(P<0.05),平均出血量明显少于传统组胃癌手术者(P<0.05);腔镜组胃癌手术者肺部感染、吻合口狭窄、肠梗阻、切口感染、腹腔感染、皮下气肿等并发症发生率明显低于传统组(P<0.05);两组平均手术时间、3年复发率相比差异无统计学意义(P>0.05)。结论腹腔镜辅助全胃切除术治疗胃癌患者更有利于提升患者日常生活能力,且不会造成复发率升高,具有良好的治疗效果。Objective To explore the effect of laparoscopic assisted total gastrectomy and traditional surgical treatment on the daily living ability and recurrence rate of gastric cancer patients.Methods A total of 60 patients with gastric cancer admitted to our hospital from January 2017 to December 2019 were selected as the study subjects.They were divided into two groups according to the different treatments:the endoscopic group(30 cases)and the traditional group(30 cases).The traditional group of patients was treated by traditional surgery,and the endoscopic group of patients was treated by laparoscopy-assisted total gastrectomy.Compare the improvement of activity of daily living(ADL)score,various surgical indicators(including operation time,anal exhaust time,intraoperative bleeding,and hospitalization time),and serological indicators(including CEA,CA199,CA125)of the two groups of gastric cancer patients before and after treatment,the incidence of complications(including lung infection,anastomotic stenosis,intestinal obstruction,incision infection,abdominal infection,subcutaneous emphysema)and the 3-year recurrence rate.Results There was no significant difference between the preoperative CEA,CA199,CA125 and ADL scores of gastric cancer patients in the two groups(P>0.05).The postoperative serological indexes and ADL scores were significantly improved(P<0.05),and the improvement of CEA,CA199,CA125 and ADL scores in the endoscopic group was significantly better than that in the traditional group(P<0.05).The anal exhaust time and hospital stay of gastric cancer patients in the endoscopic group were significantly shorter than those in the traditional group(P<0.05),and the average bleeding volume was significantly lower than those in the traditional group(P<0.05),and the incidence of complications such as lung infection,anastomotic stenosis,intestinal obstruction,incision infection,abdominal infection,subcutaneous emphysema in the endoscopic group was significantly lower than those in the traditional group(P<0.05).There was n
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