Progress towards dog-mediated rabies elimination in PR China:a scoping review  

作　　者：Tianren Shen Susan Christina Welburn Long Sun Guo-Jing Yang 

机构地区：[1]Key Laboratory of Tropical Translational Medicine of Ministry of Education,The School of Tropical Medicine,The First Affiliated Hospital,Hainan Medical University,Haikou,571199,Hainan,People’s Republic of China [2]Zhejiang University-University of Edinburgh Joint Institute,Zhejiang University,International Campus,718 East Haizhou Road,Haining,314400,People’s Republic of China [3]Infection Medicine,Deanery of Biomedical Sciences,Edinburgh Medical School,College of Medicine and Veterinary Medicine,The University of Edinburgh,1 George Square,Edinburgh,EH89JZ,Scotland,UK [4]Department of Infectious Diseases,The First Affiliated Hospital of Hainan Medical University,Hainan Medical University,Haikou,Hainan,People’s Republic of China

出　　处：《Infectious Diseases of Poverty》2023年第2期19-35,共17页贫困所致传染病（英文）

基　　金：GY is grateful to the National Natural Science Foundation(Grant no.82260655);Hainan Provincial Natural Science Foundation(Grant no.821CXTD440);the Open Foundation of Key Laboratory of Tropical Translational Medicine of Ministry of Education(ZDKJ202003);Hainan Medical University,as well as National Key Research and Development Program of China(No.2021YFC2300800,2021YFC2300804).

摘　　要：Background Rabies continues to be a serious threat to global public health endangering people’s health and public health safety.In the People’s Republic of China,multi-sectoral and comprehensive prevention and control strategies have aimed to extensively curb human rabies transmission.Here,we examine the current state of rabies infection in China,explore strategic interventions put in place in response to WHO’s ambition of“Zero rabies deaths by 2030”and critically assess the constraints and feasibility of dog-mediated rabies elimination in China.Methods This study analyzed and evaluated the process towards dog-mediated rabies elimination in China from five perspectives:namely,human,dog,policy,challenge,and prospects.Evidence-based data on progress of dog-mediated rabies elimination in China was derived from a number of sources;a literature search was undertaken using PubMed,Web of Science and CNKI databases,distribution data for human rabies cases as derived from the Data-center of the China Public Health Science and policy and document data were obtained from official websites of the relevant China ministries and commissions.Results The incidence of human rabies cases in China have shown a downward trend year-on-year since 2007.Implementation of a government-led,multi-sectoral“One Health”approach to combating rabies has driven down the total number of rabies deaths nationwide to around 200 in 2020.The number of provincial-level administrative divisions(PLADs)reporting human cases of rabies has also decreased to 21 in 2020,13 of which reported less than 10 cases.Furthermore,the number of outpatient visits seeking rabies post-exposure prophylaxis has risen dramatically over the past two decades,with demand being 15 times higher than it was initially.There remain however,significant gaps in rabies elimination outcomes across the different regions of China.To date the target of achieving a canine rabies vaccination rate of>75%has not been met.The challenges of rabies immunization of dogs and dog manage

关 键 词：RABIES LYSSAVIRUS China ELIMINATION DOG EPIDEMICS One Health Neglected Tropical UNDERREPORTING 

分 类 号：R512.99[医药卫生—内科学] R181.3[医药卫生—临床医学]