基于重症喂养流程的早期肠内营养治疗对AECOPD合并呼吸衰竭患者的应用研究  

Study on the Application of Early Enteral Nutrition Therapy Based on Critical Care Feeding Process for Patients with AECOPD Combined with Respiratory Failure

作　　者：刘怡敏[1] LIU Yimin(Department of Intensive Care Medicine,Daqing Oilfield General Hospital,Daqing,Heilongjiang Province,163001 China)

机构地区：[1]大庆油田总医院重症医学科,黑龙江大庆163001

出　　处：《中外医疗》2023年第9期80-83,共4页China & Foreign Medical Treatment

摘　　要：目的探讨基于重症喂养流程的早期肠内营养治疗在慢阻肺急性加重期(acute exacerbation of chronic obstructive pulmonary disease,AECOPD)合并呼吸衰竭患者中的治疗效果。方法随机选取2020年1月—2021年5月大庆油田总医院重症科收治的50例AECOPD合并呼吸衰竭患者为研究对象,以随机数表法分为对照组(25例)与观察组(25例)。对照组给予常规早期肠内营养治疗,观察组采用基于重症喂养流程的早期肠内营养治疗,持续治疗14 d。对比两组患者营养指标、炎症因子水平、心肺功能及恢复情况。结果治疗前,两组营养指标、炎症水平、心肺功能对比,差异无统计学意义(P>0.05);治疗后,观察组血清白蛋白(ALB)水平、总蛋白(TP)水平高于对照组,肿瘤坏死因子-α(TNF-α)水平、超敏C反应蛋白(hs-CRP)水平低于对照组,左心射血分数(LVEF)水平、血氧分压(PaO_(2))水平高于对照组,血二氧化碳分压(PaCO_(2))水平低于对照组,差异有统计学意义(P<0.05)。观察组机械通气时间(9.09±2.13)d、ICU住院时间(14.81±2.66)d短于对照组,差异有统计学意义(t=4.943、4.155,P<0.001)。结论基于重症喂养流程的早期肠内营养治疗能改善AECOPD合并呼吸衰竭患者营养状态,降低炎症水平,促进心肺功能恢复。Objective To investigate the therapeutic effect of early enteral nutrition therapy based on the critical care feeding process in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD)combined with respiratory failure.Methods 50 AECOPD patients with respiratory failure admitted to the Intensive Care Department of Daqing Oilfield General Hospital from January 2020 to May 2021 were selected randomly as the study subjects.They were randomly divided into a control group(25 cases)and an observation group(25 cases)using a random number table method.The control group received routine early enteral nutrition treatment,while the observation group received early enteral nutrition treatment based on the severe feeding process,for 14 d.Compared the nutritional indicators,inflammatory factor levels,cardiopulmonary function,and recovery between the two groups of patients.Results There was no statistically significant difference in nutritional indicators,inflammation levels,and cardiopulmonary function between the two groups before treatment(P>0.05);after treatment,the levels of serum albumin(ALB)and total protein(TP)in the observation group were higher than those in the control group,the levels of tumor necrosis factor-α(TNF-α),high sensitivity C-reactive protein(hs-CRP)were lower than those of the control group,while left ventricular ejection fraction(LVEF)and the levels of blood oxygen partial pressure(PaO_(2))were higher than those of the control group,partial pressure of carbon dioxide(PaCO_(2))was lower than the control group,the difference was statistically significant(P<0.05).The mechanical ventilation time(9.09±2.13)d and ICU hospitalization time(14.81±2.66)d in the observation group were shorter than those in the control group,the difference was statistically significant(t=4.943,4.155,P<0.001).Conclusion Early enteral nutrition therapy based on the critical care feeding process can improve the nutritional status of patients with AECOPD combined with respiratory failure,reduce the level of

关 键 词：慢阻肺 重症喂养流程 早期肠内营养治疗 营养指标 

分 类 号：R5[医药卫生—内科学]