妊娠期缺铁性贫血患者SF、TRF指标与围生期结局的相关性分析及临床意义  

Correlation Analysis and Clinical Significance of SF,TRF and Perinatal Outcome in Patients with Iron Deficiency Anemia during Pregnancy

作　　者：陈娟芳 CHEN Juanfang(Department of Obstetrics and Gynecology,Fuqing Fifth Hospital,Fuqing 350319,China)

机构地区：[1]福清市第五医院妇产科,福建福州350319

出　　处：《中国医药指南》2023年第16期125-127,共3页Guide of China Medicine

摘　　要：目的分析妊娠期缺铁性贫血患者血清铁蛋白(SF)、血清转铁蛋白(TRF)指标与围生期结局的相关性及临床意义。方法将2020年8月至2022年8月到医院诊治的43例妊娠期缺铁性贫血患者纳入研究组,另选择同时间段内就诊的43例妊娠期正常女性纳入对照组,两组均接受血清SF、TRF检测。对比两组的SF、TRF水平,观察两组的围生期结局,分析血清SF、TRF与围生期结局的相关性及临床意义。结果研究组的血清SF水平低于对照组,TRF水平高于对照组(P<0.05)。在不良围生期结局发生率方面,研究组高于对照组(P<0.05)。胎儿生长受限、胎儿窘迫、早产及产后出血患者的血清SF水平显著低于非胎儿生长受限、胎儿窘迫、早产及产后出血患者,TRF水平高于非胎儿生长受限、胎儿窘迫、早产及产后出血患者,对比差异有统计学意义(P<0.05)。围生期结局良好组的血清SF水平高于围生期结局不良组,TRF水平低于围生期结局不良组(P<0.05)。妊娠期缺铁性贫血患者ST水平与不良围生期结局呈正相关关系,TRF水平与不良围生期结局呈负相关关系(P<0.05)。结论血清SF、TRF水平与妊娠期缺铁性贫血患者的围生期结局具有相关性,可将其作为诊断妊娠期缺铁性贫血的辅助指标。Objective To analyze the correlation and clinical significance between serum ferritin(SF),serum transferrin(TRF)and perinatal outcome in patients with iron deficiency anemia during pregnancy.Methods Forty-three patients with iron deficiency anemia during pregnancy who were treated in the hospital from August 2028 to August 2028 were included in the study group,and 43 normal pregnant women in the same period were included in the control group.Both groups received serum SF and TRF tests.Compare the levels of SF and TRF in the two groups,observe the perinatal outcomes of the two groups,and analyze the correlation and clinical significance between serum SF and TRF and perinatal outcomes.Results The serum SF of the study group was lower than that of the control group,and the TRF was higher than that of the control group(P<0.05).The incidence of adverse perinatal outcomes in the study group was higher than that in the control group(P<0.05).The serum SF levels were significantly lower in patients with fetal growth restriction,fetal distress,preterm delivery and postpartum hemorrhage than in patients with non-fetal growth restriction,fetal distress,preterm delivery and postpartum hemorrhage,and TRF was higher than in patients with non-fetal growth restriction,fetal distress,preterm delivery and postpartum hemorrhage,with significant differences in comparison(P<0.05).The serum SF in the group with good perinatal outcome was higher than that in the group with poor perinatal outcome,and the TRF was lower than that in the group with poor perinatal outcome(P<0.05).There was a positive correlation between ST level and adverse perinatal outcome in patients with iron deficiency anemia during pregnancy,and a negative correlation between TRF and adverse perinatal outcome(P<0.05).Conclusion The serum SF and TRF are correlated with the perinatal outcome of patients with iron deficiency anemia during pregnancy,which can be used as auxiliary indicators for diagnosis of iron deficiency anemia during pregnancy.

关 键 词：妊娠期缺铁性贫血 血清铁蛋白 血清转铁蛋白 围生期结局 

分 类 号：R714.25[医药卫生—妇产科学]