Design of portable electrochemiluminescence sensing systems for point-of-care-testing applications  

作　　者：Shuqi Xia Jiangfei Pan Deshen Dai Zong Dai Mengsu Yang Changqing Yi 

机构地区：[1]Guangdong Provincial Engineering and Technology Center of Advanced and Portable Medical Devices,School of Biomedical Engineering,Sun Yat-sen University,Shenzhen 518107,China [2]Research Institute of Sun Yat-sen University in Shenzhen,Shenzhen 518057,China [3]Department of Biomedical Sciences&Tung Biomedical Sciences Centre,City University of Hong Kong,Hong Kong,China

出　　处：《Chinese Chemical Letters》2023年第5期88-103,共16页中国化学快报（英文版）

基　　金：The financial support from the National Key Research and Development Program of China(No.2022YFE0201800);Shenzhen Science and Technology Innovation Commission(Nos.GJHZ20210705142200001 and JCYJ20210324140004013);Guangdong Natural Science Foundation(Nos.2021A1515220020 and 2020B1212060077)is gratefully acknowledged。

摘　　要：Point-of-care testing(POCT)technology is highly desirable for clinical diagnosis,healthcare monitoring,food safety inspection,and environment surveillance,because it enables rapid detection anywhere,anytime,and by anyone.Electrochemiluminescence(ECL)has been widely used in chemo-/bio analysis due to its advantages such as high sensitivity,simplicity,rapidity and easy to control,and is now attracting increasing attention for POCT applications.However,to realize the accurate on-site quantitation,it is still challenging to develop portable devices which can precisely collect,analyze,transmit and display the ECL signals.This review will focus on how to develop a portable ECL device by summarizing recent examples and analyzing their key components part by part.Then the possible solutions to the existing challenges in the development and applications of portable ECL devices are summarized and discussed in detail,followed by offering future perspectives.We attempted to provide an appealing viewpoint to inspire interested researchers to comprehend and explore portable ECL sensing systems for practical applications and even commercialization.

关 键 词：SMARTPHONE Screen-printed electrode Bipolar electrode Machine learning Aggregation-induced ECL Nanoscale ECL luminophores MICROFLUIDICS 

分 类 号：TP212[自动化与计算机技术—检测技术与自动化装置] O657.1[自动化与计算机技术—控制科学与工程]