Efficient synthesis of cyclic imides by the tandem N-arylation-acylation and rearrangement reaction of cyanoesters with diaryliodonium salts  

作　　者：Zhiyuan Bao Chao Chen 

机构地区：[1]MOE Key Laboratory of Bioorganic Phosphorus Chemistry&Chemical Biology,Department of Chemistry,Tsinghua University,Beijing 100084,China

出　　处：《Chinese Chemical Letters》2023年第5期281-285,共5页中国化学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China(Nos.21871158 and 22071129)。

摘　　要：Available online An efficient method for the synthesis of multi-substituted cyclic imides was developed with cyanoesters and diaryliodonium salts.This method proceeds through a cascade of N-arylationacylation and rearrangement to give target heterocycles in good yields(up to 99%).This method has the major advantages of a broad substrate scope,excellent functional group compatibility.The strategy was also extended to the fused cyclic imides,such as malonimides,succinimides and glutarimides.

关 键 词：Cyclic imides Cyanoesters Diaryliodonium salts N-Arylation-acylation REARRANGEMENT 

分 类 号：TQ236[化学工程—有机化工]