银杏叶滴丸联合缬沙坦胶囊治疗老年高血压患者的效果观察  

Effect of ginkgo biloba dropping pills combined with valsartan capsules in treatment of elderly patients with hypertension

作　　者：刘宁 郑学燕[2] 董敏[3] 孙宝莲 Liu Ning;Zheng Xueyan;Dong Min;Sun Baolian(Clinic,Department of General Medicine,Jinan Second People's Hospital,Jinan 250001,China;Department of Pharmacy,Jinan Second People's Hospital,Jinan 250001,China;Department of Internal Medicine,Jinan Second People's Hospital,Jinan 250001,China;Department of Internal Medicine,Jinan Zhongqi Hospital,Jinan 250031,China)

机构地区：[1]济南市第二人民医院全科门诊,济南250001 [2]济南市第二人民医院药学部,济南250001 [3]济南市第二人民医院内科,济南250001 [4]济南重汽医院内科,济南250031

出　　处：《国际医药卫生导报》2023年第12期1674-1677,共4页International Medicine and Health Guidance News

基　　金：山东省自然科学基金(ZR2019MH064)。

摘　　要：目的观察银杏叶滴丸联合缬沙坦胶囊治疗老年高血压患者的效果。方法选取2020年1月至2021年12月济南市第二人民医院收治的老年高血压患者116例进行随机对照试验,采用随机数字表法将其分为联合治疗组和基础治疗组,各58例。基础治疗组男38例,女20例,年龄(70.23±3.51)岁。联合治疗组男39例,女19例,年龄(70.92±3.67)岁。基础治疗组采用银杏叶滴丸治疗,联合治疗组采用银杏叶滴丸联合缬沙坦胶囊治疗。对比两组患者治疗前后血压、临床疗效、治疗期间不良反应发生率。采用t检验、Z检验和χ^(2)检验。结果两组治疗后舒张压和收缩压均低于治疗前(均P<0.05);治疗后,联合治疗组舒张压和收缩压均低于基础治疗组(均P<0.05)。联合治疗组总有效率为96.55%(56/58),明显高于基础治疗组的72.41%(42/58)(P<0.05)。联合治疗组治疗期间不良反应发生率与基础治疗组比较,差异无统计学意义(P>0.05)。结论银杏叶滴丸联合缬沙坦胶囊治疗老年高血压能够有效提高临床疗效,且能够降低患者舒张压、收缩压,且具有安全性,值得推广使用。Objective To observe the effect of ginkgo biloba dropping pills combined with valsartan capsules in the treatment of elderly patients with hypertension.Methods A total of 116 elderly patients with hypertension admitted to Jinan Second People's Hospital from January 2020 to December 2021 were selected for the randomized controlled trial.The patients were divided into a combined treatment group and a basic treatment group by the random number table method,with 58 cases in each group.There were 38 males and 20 females in the basic treatment group;they were(70.23±3.51)years old.There were 39 males and 19 females in the combined treatment group;they were(70.92±3.67)years old.The basic treatment group were treated with ginkgo biloba dropping pills,and the combined treatment group with ginkgo biloba dropping pills and valsartan capsules.The blood pressures before and after the treatment,clinical efficacies,and incidences of adverse reactions during the treatment were compared between the two groups.t,Z,andχ^(2) tests were applied.Results The diastolic blood pressures and systolic blood pressures in the 2 groups were lower after than before the treatment(all P<0.05);after the treatment,the diastolic blood pressure and systolic blood pressure in the combined treatment group were lower than those in the basic treatment group(both P<0.05).The total effective rate of the combined treatment group was significantly higher than that of the basic treatment group[96.55%(56/58)vs.72.41%(42/58);P<0.05].There was no statistical difference in the incidence of adverse reactions during the treatment between the combined treatment group and the basic treatment group(P>0.05).Conclusion Ginkgo biloba dripping pills combined with valsartan capsules in the treatment of elderly patients with hypertension can effectively improve the clinical efficacy and reduce their diastolic and systolic blood pressures,and is safe,so it is worthy of promotion.

关 键 词：老年高血压 银杏叶滴丸 缬沙坦胶囊 临床疗效 舒张压 收缩压 

分 类 号：R544.1[医药卫生—心血管疾病]