贮存式与回收式自体输血应用于骨科择期手术的疗效研究  

Study on the efficacy of stored and recovered autotransfusion in orthopedic elective surgery

作　　者：黄爱群[1] 魏淑贞 陈惠红 叶思城 孙凯 Huang Aiqun;Wei Shuzhen;Chen Huihong;Ye Sicheng;Sun Kai(Department of Blood Transfusion,The Fifth Affiliated Hospital of Guangzhou Medical University,Guangzhou 510700,China)

机构地区：[1]广州医科大学附属第五医院输血科,广州510700

出　　处：《国际医药卫生导报》2023年第11期1537-1540,共4页International Medicine and Health Guidance News

基　　金：广东省医学科研基金(C2021078)。

摘　　要：目的探讨贮存式与回收式自体输血在骨科非肿瘤择期手术中应用的疗效和安全性。方法回顾分析2021年7月至2022年6月广州医科大学附属第五医院骨科诊断为非肿瘤疾病的择期手术40例,根据输血方式分为试验组和对照组,每组20例。试验组男8例、女12例,年龄(60.75±23.26)岁,接受贮存式和回收式自体输血;对照组男12例、女8例,年龄(57.00±16.95)岁,接受异体输血。对比两组血红蛋白(hemoglobin,Hb)、红细胞压积(hematocrit,HCT)、血小板计数(platelet,PLT)、凝血酶原时间(prothrombin time,PT)、活化部分凝血活酶时间(activated partial thromboplastin time,APTT)、纤维蛋白原(fibrinogen,FIB)、输血量、总住院天数、术后住院天数和输血相关不良反应的差异。采用t检验、χ^(2)检验。结果试验组和对照组在Hb、HCT、PLT、APTT、PT、FIB、输血量、总住院天数、术后住院天数上,差异均无统计学意义(均P>0.05)。结论相比于异体输血,贮存式和回收式自体输血应用于骨科择期手术安全且有效,对加强围手术期患者血液管理、保障患者手术安全和临床输血安全具有重要意义。Objective To investigate the efficacy and safety of stored and recovered autotransfusion in orthopedic non-tumor elective surgery.Methods A retrospective analysis was conducted on 40 cases of elective surgery diagnosed as non-tumor diseases in the orthopedic department of the Fifth Affiliated Hospital of Guangzhou Medical University from July 2021 to June 2022,who were divided into an experimental group and a control group,with 20 cases in each group.There were 8 males and 12 females in the experimental group,aged(60.75±23.26)years;there were 12 males and 8 females in the control group,aged(57.00±16.95)years.The experimental group received stored and recovered autotransfusion,while the contr ol group received allogeneic blood transfusion.The differences in hemoglobin(Hb),hematocrit(HCT),platelet(PLT),prothrombin time(PT),activated partial thromboplastin time(APTT),fibrinogen(FIB),blood transfusion volume,total hospital stay,postoperative hospital stay,and transfusion-related adverse reactions were compared between the two groups.t test andχ^(2) test were used.Results There were no statistically significant differences in the Hb,HCT,PLT,APTT,PT,FIB,blood transfusion volume,total hospital stay,and postoperative hospital stay between the experimental group and the control group(all P>0.05).Conclusion Compared with allogeneic blood transfusion,stored and recovered autotransfusion is safe and effective in orthopedic elective surgery,which is of great significance to strengthen the patients'blood management during perioperative period and ensure the safety of surgery and clinical blood transfusion.

关 键 词：贮存式自体输血 回收式自体输血 异体输血 骨科 择期手术 安全 

分 类 号：R687.3[医药卫生—骨科学] R457.1[医药卫生—外科学]