连朴饮联合阿米卡星、左氧氟沙星治疗急性重症细菌感染性腹泻的疗效分析  

Analysis of the Efficacy of Combining Amikacin and Levofloxacin in the Treatment of Acute Severe Bacterial Infectious Diarrhea with Lianpu Drink

作　　者：刘成 LIU Cheng(Department of Infection,Shangqiu Municipal Hospital,Shangqiu,Henan,476000,China)

机构地区：[1]商丘市立医院感染科,河南商丘476000

出　　处：《黑龙江医学》2023年第12期1456-1458,共3页Heilongjiang Medical Journal

摘　　要：目的:探究连朴饮联合阿米卡星、左氧氟沙星治疗急性重症细菌感染性腹泻的疗效。方法:选取2018年10月—2020年10月商丘市立医院收治的110例急性重症细菌感染性腹泻患者作为研究对象。采用随机分组方法将患者分为观察组和对照组,每组各55例。所有患者均给予常规基础治疗,对照组采用左氧氟沙星联合阿米卡星静脉滴注,观察组在对照组的基础上加以口服中药连朴饮治疗。观察两组患者治疗后临床疗效、病症改善时间(发热、呕吐、腹痛、腹泻)、临床常规检查结果(白细胞、脓细胞、红细胞)。结果:治疗后观察组血常规中白细胞增多比率低于对照组,粪便常规中白细胞、脓细胞和红细胞转阴率高于对照组,差异有统计学意义(χ^(2)=4.853、4.853、4.274、4.950,P<0.05);观察组治疗后临床总有效率高于对照组,差异有统计学意义(χ^(2)=4.950,P<0.05);观察组发热、呕吐、腹痛、腹泻等临床病症改善时间均短于对照组,差异有统计学意义(t=2.759、4.076、5.539、4.029,P<0.05)。结论:使用连朴饮联合阿米卡星、左氧氟沙星治疗急性重症感染性腹泻能够缩短病症改善时间、改善血常规及粪便常规检查结果,疗效显著。Objective:To investigate the efficacy of Lianpu Drink combined with amikacin and levofloxacin in the treatment of acute severe bacterial infectious diarrhea.Methods:110 patients with acute severe bacterial infectious diarrhea admitted to the hospital from October 2018 to October 2020 were selected as the study subjects,and the patients were divided into observation and control groups according to the random grouping method,with 55 cases in each group.All patients were given conventional basic treatment,and the control group was treated with levofloxacin combined with amikacin intravenously,while the observation group was treated with oral Chinese herbal medicine Lianpu Drink on the basis of the control group.The clinical efficacy,time of improvement of disease(fever,vomiting,abdominal pain,diarrhea),and clinical routine examination results(white blood cells,pus cells,red blood cells)after treatment were observed in both groups.Results:The rate of leukocytosis in blood routine was lower in the observation group than in the control group after clinical treatment,and the rate of conversion of leukocytes,pus cells and red blood cells in stool routine was higher than in the control group,with statistically significant differences(χ^(2)=4.853,4.853,4.274,4.950,P<0.05).The total clinical efficiency after treatment was higher in the observation group than in the control group,and the difference was statistically significant(χ^(2)=4.950,P<0.05).The improvement time of clinical symptoms such as fever,vomiting,abdominal pain and diarrhea was shorter in the observation group than in the control group,and the difference was statistically significant(t=2.759,4.076,5.539,4.029,P<0.05).Conclusion:The treatment of acute severe infectious diarrhea with Lianpu drink combined with amikacin and levofloxacin was effective in shortening the improvement time of the disease and improving the results of routine blood and fecal tests.

关 键 词：连朴饮 急性重症感染性腹泻 左氧氟沙星 阿米卡星 

分 类 号：R512.5[医药卫生—内科学]