光诱导铁催化在有机合成中的应用研究进展  

Recent Development of Photoinduced Iron-Catalysis in Organic Synthesis

作　　者：窦谦 汪太民 房丽晶[1,2] 翟宏斌 程斌 Dou Qian;Wang Taimin;Fang Lijing;Zhai Hongbin;Cheng Bin(Institute of Biomedicine and Biotechnology,Shenzhen Institute of Advanced Technology,Chinese Academy of Sciences,Shenzhen,Gugangdong 518055;Institute of Marine Biomedicine/Postdoctoral Innovation Practice Base,Shenzhen Polytechnic,Shenzhen,Gugangdong 518055;State Key Laboratory of Chemical Oncogenomics,Peking University Shenzhen Graduate School,Shenzhen,Gugangdong 518055)

机构地区：[1]中国科学院深圳先进技术研究院/生物医药与技术研究所,广东深圳518055 [2]深圳职业技术学院/海洋生物医药研究院,广东深圳518055 [3]北京大学深圳研究生院/肿瘤化学基因组学国家重点实验室,广东深圳518055

出　　处：《有机化学》2023年第4期1386-1415,共30页Chinese Journal of Organic Chemistry

基　　金：广东省教育厅产教融合创新平台(No.6021210004P);广东省教育厅创新团队(No.2021KCXTD069);深圳职业技术学院深圳市高端人才科研启动项目(No.6022310047k);深圳职业技术学院博士后基金(No.6021330006K)资助项目;深圳市科技创新委员会(Nos.JSGG20201103153800002,GJHZ20200731095412037,JCYJ20200109141808025)。

摘　　要：近年来,以过渡金属钌和铱络合物为代表的光催化剂的开发和应用为有机合成开启了新篇章,这些过渡金属光催化剂参与的光催化反应为化学键的构筑和有机转化提供了温和高效的新策略.为了丰富光催化剂的种类,拓宽光催化体系的适用范围,发展绿色可持续化学,近年来一些廉价易得的过渡金属比如铜、铁等被相继开发用作光催化剂.其中,铁催化剂因其无毒、种类丰富,并且具有独特的配体-金属电荷转移性质,在光催化合成领域大放异彩.依据反应类型对光诱导铁催化反应进行了综述,主要包括C—H键官能团化反应、C-C键官能团化反应、烯烃双官能团化反应、交叉偶联反应、脱羧官能团化反应、选择性氧化和还原反应.In recent years,the development and application of transition metal ruthenium or iridium complexes based photocatalysts have opened up a new research field for organic synthesis,which provides mild and efficient strategies for the construction of chemical bonds and organic transformations.In order to enrich the types of photocatalysts,broaden the application scope of photocatalysis,and develop green and sustainable chemistry,some low-cost and easily available organometallic complexes with copper or iron were applied as photocatalysts recently.Iron-complexes feature non-toxicity,rich variety,and unique property of charge transfer from ligands to metals,which enable them show extraordinary capability in the field of photocatalytic synthesis.According to different reaction types,this review focuses on the recent development of photoinduced iron-catalysis in organic synthesis including C-H bond functionalization,C-C bond functionalization,bifunctionalization of alkenes,cross-coupling reaction,decarboxylative functionalization,selective oxidation and reduction.

关 键 词：光化学 铁催化 自由基 绿色化学 有机合成 

分 类 号：O621.3[理学—有机化学] O643.36[理学—化学] O644.1