头穴丛刺治疗阿尔茨海默病抑郁症状的疗效观察  

Therapeutic observation of scalp-point clustering acupuncture for depressive symptoms in Alzheimer’s disease

作　　者：王春霞[1] 田芃 崔乃松[1] 邢继杰[1] WANG Chunxia;TIAN Peng;CUI Naisong;XING Jijie(Second Affiliated Hospital,Heilongjiang University of Chinese Medicine,Harbin 150001,China)

机构地区：[1]黑龙江中医药大学附属第二医院,哈尔滨150001

出　　处：《上海针灸杂志》2023年第6期582-587,共6页Shanghai Journal of Acupuncture and Moxibustion

基　　金：黑龙江省自然科学基金面上项目(H2017070)。

摘　　要：目的观察头穴丛刺治疗阿尔茨海默病抑郁症状的临床疗效。方法将60例阿尔茨海默病伴抑郁症状的患者随机分为治疗组(30例,脱落2例)和对照组(30例,脱落1例)。两组均予口服盐酸多奈哌齐片治疗,对照组予常规针刺治疗,治疗组在常规针刺治疗基础上联合头穴丛刺治疗。分别于治疗前后观察并记录两组简易精神状态评价量表(mini-mental stateexamination,MMSE)、康奈尔痴呆抑郁量表(Cornellscale for depression in dementia,CSDD)和汉密尔顿抑郁量表(Hamilton depression scale,HAMD)的评分变化,比较两组临床疗效。结果治疗组总有效率为85.7%,优于对照组的72.4%,差异具有统计学意义(P<0.05)。两组治疗后HAMD和CSDD评分均较同组治疗前降低(P<0.05),MMSE评分较同组治疗前升高(P<0.05);且治疗组治疗后上述3项评分均优于对照组(P<0.05)。结论在药物治疗基础上,头穴丛刺联合常规针刺治疗阿尔茨海默病抑郁症状疗效优于单纯常规针刺治疗,可进一步改善患者的抑郁情绪,提高患者认知功能。Objective To observe the clinical efficacy of scalp-point clustering acupuncture in treating depressive symptoms in Alzheimer’s disease.Method Sixty Alzheimer’s disease patients presenting depressive symptoms were randomized into a treatment group(30 cases including 2 dropouts)and a control group(30 cases including 1 dropout).Both groups received oral administration of Donepezil hydrochloride tablets;in addition,the control group was given the ordinary acupuncture treatment,and the treatment group was offered the ordinary acupuncture treatment plus scalp-point clustering acupuncture.Before and after treatment,the mini-mental state examination(MMSE),Cornell scale for depression in dementia(CSDD),and Hamilton depression scale(HAMD)scores were observed and recorded.The clinical efficacy was compared between the two groups.Result The total effective rate was 85.7%in the treatment group,better than 72.4%in the control group,and the between-group difference was statistically significant(P<0.05).After treatment,the HAMD and CSDD scores dropped in both groups(P<0.05),and the MMSE score increased(P<0.05);the treatment group was superior to the control group in comparing the three scales(P<0.05).Conclusion Based on pharmaceutical intervention,scalp-point clustering acupuncture plus ordinary acupuncture can produce more significant efficacy in treating depressive symptoms in Alzheimer’s disease than ordinary acupuncture alone;this combination treatment can further improve depressive mood and cognitive function.

关 键 词：针刺疗法 针药并用 头针 阿尔茨海默病 痴呆 抑郁 

分 类 号：R246.6[医药卫生—针灸推拿学]