针药并用治疗肾精亏虚型免疫性血小板减少症的疗效观察  

Observation on the therapeutic effect of acupuncture combined with medicines in the treatment of immune thrombocytopenia of kidney essence deficiency pattern

作　　者：项琼瑶[1,2] 徐旻 曹左媛 孙慧平[1] 李希 姚晔[2,3] 沈伟 XIANG Qiongyao;XU Min;CAO Zuoyuan;SUN Huiping;LI Xi;YAO Ye;SHEN Wei(Ruijin Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200025,China;Shanghai Famous TCM Doctor Yao Naizhong Studio,Shanghai 200032,China;Longhua Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China)

机构地区：[1]上海交通大学医学院附属瑞金医院,上海200025 [2]上海市名中医姚乃中工作室,上海200032 [3]上海中医药大学附属龙华医院,上海200032

出　　处：《上海针灸杂志》2023年第6期622-626,共5页Shanghai Journal of Acupuncture and Moxibustion

基　　金：上海市进一步加快中医药事业发展三年行动计划中医特色诊疗技术提升项目[ZY(2018-2020)-ZYJS-22];上海市名中医姚乃中工作室医疗专项(No.YW004.020)。

摘　　要：目的观察针灸联合上海市名中医姚乃中教授经验方治疗肾精亏虚型慢性免疫性血小板减少症(immune thrombocytopenia,ITP)的临床疗效。方法将100例肾精亏虚型慢性ITP患者随机分为治疗组和对照组,每组50例。两组患者均接受西药治疗且治疗方案保持不变,治疗组在此基础上另予针灸联合上海市名中医姚乃中教授经验方治疗。观察两组治疗前后外周血血小板计数和网织血小板比率以及出血评分的变化,比较两组临床疗效和不良反应发生情况。结果治疗后,两组外周血血小板计数均较治疗前上升(P<0.01),且治疗组高于对照组(P<0.01);两组外周血网织血小板比率和出血评分均较治疗前下降(P<0.01),且治疗组低于对照组(P<0.01)。治疗组总有效率为97.8%,对照组为80.0%,组间差异具有统计学意义(P<0.01)。两组治疗过程中均未见明显不良反应。结论在西药治疗基础上,针灸联合上海市名中医姚乃中教授经验方治疗肾精亏虚型慢性免疫性血小板减少症可升高外周血小板计数,降低网织血小板比率,改善临床出血症状,提高疗效。Objective To observe the clinical effect of acupuncture and moxibustion combined with Professor Yao Naizhong’s empirical formula in the treatment of chronic immune thrombocytopenia(ITP)of kidney essence deficiency pattern.Method A total of 100 chronic ITP patients with kidney essence deficiency pattern were randomly divided into a treatment group and a control group,with 50 cases in each group.Both groups were treated with Western medicine,and the treatment regimen remained unchanged.In addition,the treatment group was treated with acupuncture and moxibustion combined with Professor Yao Naizhong’s empirical formula.The changes of peripheral blood platelet count,reticulocyte ratio and bleeding score before and after treatment were observed in the two groups.The clinical efficacy and adverse reactions were compared between the two groups.Result After treatment,the peripheral blood platelet count increased in both groups compared with that before treatment(P<0.01),and was higher in the treatment group than in the control group(P<0.01);the peripheral blood reticulocyte ratio and bleeding score decreased in both groups compared with that before treatment(P<0.01),and was lower in the treatment group than in the control group(P<0.01).The overall effective rate was 97.8%in the treatment group and 80.0%in the control group,with a statistically significant difference between the groups(P<0.01).No significant adverse effects were observed during the treatment in both groups.Conclusion In addition to the Western medicine treatment,acupuncture and moxibustion combined with Professor Yao Naizhong’s empirical formula in the treatment of chronic ITP of kidney essence deficiency pattern can increase the peripheral platelet count,reduce the reticulocyte ratio,improve the clinical bleeding symptoms,and improve the therapeutic effect.

关 键 词：针刺疗法 艾条灸 针药并用 肾精亏虚 紫癜 血小板减少性 特发性 

分 类 号：R246.1[医药卫生—针灸推拿学]