Ventricular Septal Crypts:Remnants of Spontaneous Interventricular Defect Closure?  

作　　者：Alberto Cresti Stefania Sparla Stefania Stefanelli Andrea Picchi Ugo Limbruno 

机构地区：[1]Cardiology Unit,Misericordia Hospital,Grosseto,Italy

出　　处：《Congenital Heart Disease》2023年第1期1-6,共6页先天性心脏病（英文）

摘　　要：Background:Ventricular crypts are quite a common finding during cardiac imaging,but their etiology is unclear.A possible final result of a spontaneous ventricular septal defect closure has been supposed but never investigated in earlier studies.Method:From January 1997 to December 2020,all newborns diagnosed to have a ventricular septal defect were prospectively entered in our database and those with an isolated defect were included in the study.Ventricular septal defects were classified into four types:perimembranous,trabecular muscular,inlet and outlet.A long-term follow up was performed in order to visualize the possible residual formation of a septal myocardial crypt.Results:A total of 376 isolated ventricular septal defects(314 muscular and 54 perimembranous,4 inlet,4 outlet)were detected.Follow up ranged from 1 to 23 years and showed that,among muscular type,a spontaneous closure occurred in 284(91%),26 did not close(8,28%),2 required surgical intervention(0,63%),3 were lost at follow up(0,95%).During this period,after spontaneous defect closure closure,20 crypts were found(6,4%).Conclusion:This study shows that a muscular ventricular septal defect may evolve in the 6.4%of cases in a residual septal crypt.Although septal crypts occur more frequently in patients affected by hypertrophic and hypertensive cardiomyopathy,they may also represent the evolution of a spontaneous closure of a muscular interventricular defect.

关 键 词：Ventricular crypts ventricular septal defect cardiac imaging 

分 类 号：R541[医药卫生—心血管疾病]