同种异体富血小板血浆治疗继发带状疱疹创面的探讨——附1例报道  

Secondary herpes zoster wound cured by allogeneic platelet-rich plasma:a case report

作　　者：周婉 吴磊 周济宏 顾娜 邵小宝 朱培元 ZHOU Wan;WU Lei;ZHOU Jihong;GU Na;SHAO Xiaobao;ZHU Peiyuan(Medical Cosmetology Department,Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine,Nanjing 210022,China;Department of Transfusion Medicine,Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicin)

机构地区：[1]南京市中医院医疗美容科,江苏南京210022 [2]南京市中医院输血科

出　　处：《中国输血杂志》2023年第5期436-439,共4页Chinese Journal of Blood Transfusion

基　　金：江苏省输血协会英科新创科研基金资助项目(JS2022006)。

摘　　要：目的探讨同种异体富血小板血浆(platelet-rich plasma,PRP)应用于系统性红斑狼疮继发带状疱疹伤口,尤其是大面积溃疡创面治疗的可行性。方法回顾性分析1例系统性红斑狼疮继发会阴部、臀部大面积带状疱疹创面伴广泛软组织坏死患者的治疗过程,结合治疗要点与文献复习内容,探讨同种异体PRP的临床效果。结果患者经伤口床准备至创面新鲜后外用同种异体PRP,每周使用3次,42 d后创面完全愈合。结论在自体PRP无法获得或不适合的情况下,同种异体PRP是一种较安全的替代方案,能够有效促进组织再生,本例患者在短期内达到治愈效果。Objective To investigate the feasibility of allogeneic platelet-rich plasma(PRP)for the treatment of herpes zoster wounds secondary to systemic lupus erythematosus(SLE),especially large ulcer wounds.Methods The treatment process of a patient with massive herpes zoster wounds in perineum and hip accompanied by extensive soft tissue necrosis secondary to SLE was retrospectively analyzed.The clinical efficacy of allogeneic PRP was explored combined with treatment key points and literature review.Results The patient's wound bed was prepared until the wound was fresh,then treated externally with allogeneic PRP 3 times a week.The wound was healed completely after 42 days.Conclusion In the case of autologous PRP unavailable or unsuitable,allogeneic PRP is a safe alternative,which can effectively promote tissue regeneration,and this patient achieved curative effect in a short period of time.

关 键 词：富血小板血浆 带状疱疹 系统性红斑狼疮 创面 皮肤病 

分 类 号：R457.14[医药卫生—治疗学] R752.11[医药卫生—临床医学]